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Recombinant Human ADAM15 / MDC15 Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8390
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 246

Product NumberDescriptionPrice
QP8390-ec-100ug Size: 100 ug, Tag: GST $ 398.00
QP8390-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8390-ec-10ug
Recombinant Human ADAM15 / MDC15 Protein General Information
Alternate Names
ADAM15; MDC15; AD56; MDC15
Curated Database and Bioinformatic Data
Gene SymbolADAM15
Entrez Gene ID8751
Ensemble Gene IDENSG00000143537
RefSeq Protein Accession(s)NP_001248393.1
RefSeq mRNA Accession(s)NM_001261464.1, NM_001261465.1, NM_001261466.1, NM_003815.4, NM_207191.2, NM_207194.2, NM_207195.2, NM_207196.2, NM_207197.2
UniProt ID(s)Q13444
UniGene ID(s)Hs.312098
HGNC ID(s)HGNC:193
COSMIC ID Link(s)ADAM15
KEGG Gene ID(s)hsa:8751
PharmGKB ID(s)PA24510
General Description of Recombinant Human ADAM15 / MDC15 Protein.
Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage rodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain

Human ADAM15 / MDC15 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant ADAM15 / MDC15 based upon sequence from: Human
Host: QP8390 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) ADAM15 / MDC15, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8390.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Asp207 - Thr452
Amino Acid Sequence: DVVTETKTVE LVIVADHSEA QKYRDFQHLL NRTLEVALLL DTFFRPLNVR VALVGLEAWT QRDLVEISPN PAVTLENFLH WRRAHLLPRL PHDSAQLVTG TSFSGPTVGM AIQNSICSPD FSGGVNMDHS TSILGVASSI AHELGHSLGL DHDLPGNSCP CPGPAPAKTC IMEASTDFLP GLNFSNCSRR ALEKALLDGM GSCLFERLPS LPPMAAFCGN MFVEPGEQCD CGFLDDCVDP CCDSLT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human ADAM15 / MDC15 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human ADAM15 / MDC15 Protein