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Recombinant Human GM2A Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8405
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 162

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8405-ec-10ug
Recombinant Human GM2A Protein General Information
Alternate Names
GM2A; SAP-3; GM2-AP
Curated Database and Bioinformatic Data
Gene SymbolGM2A
Entrez Gene ID2760
Ensemble Gene IDENSG00000196743
RefSeq Protein Accession(s)NP_000396.2
RefSeq mRNA Accession(s)NM_000405.4
UniProt ID(s)P17900
UniGene ID(s)Hs.483873
HGNC ID(s)HGNC:4367
COSMIC ID Link(s)GM2A
KEGG Gene ID(s)hsa:2760
PharmGKB ID(s)PA28752
General Description of Recombinant Human GM2A Protein.
The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity . Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from mbranes and presents th in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

Human GM2A Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant GM2A based upon sequence from: Human
Host: QP8405 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GM2A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8405.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ser32 - Ile193
Amino Acid Sequence: SSFSWDNCDE GKDPAVIRSL TLEPDPIIVP GNVTLSVMGS TSVPLSSPLK VDLVLEKEVA GLWIKIPCTD YIGSCTFEHF CDVLDMLIPT GEPCPEPLRT YGLPCHCPFK EGTYSLPKSE FVVPDLELPS WLTTGNYRIE SVLSSSGKRL GCIKIAASLK GI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GM2A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human GM2A Protein