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Recombinant Human Catechol O-methyltransferase Protein

$ 88.00$ 1,618.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8420
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 220

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8420-ec-10ug
Recombinant Human Catechol O-methyltransferase Protein General Information
Alternate Names
HEL-S-98n
Curated Database and Bioinformatic Data
Gene SymbolCOMT
Entrez Gene ID1312
Ensemble Gene IDENSG00000093010
RefSeq Protein Accession(s)NP_000745.1
RefSeq mRNA Accession(s)NM_000754.3, NM_001135161.1, NM_001135162.1, NM_007310.2, XM_017028594.1, XM_017028595.1
UniProt ID(s)P21964
UniGene ID(s)Hs.370408
HGNC ID(s)HGNC:2228
COSMIC ID Link(s)COMT
KEGG Gene ID(s)hsa:1312
PharmGKB ID(s)PA117
General Description of Recombinant Human Catechol O-methyltransferase Protein.
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.

Human Catechol O-methyltransferase Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Catechol O-methyltransferase based upon sequence from: Human
Host: QP8420 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Catechol O-methyltransferase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8420.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Gly52 - Pro271
Amino Acid Sequence: GDTKEQRILN HVLQHAEPGN AQSVLEAIDT YCEQKEWAMN VGDKKGKIVD AVIQEHQPSV LLELGAYCGY SAVRMARLLS PGARLITIEI NPDCAAITQR MVDFAGVKDK VTLVVGASQD IIPQLKKKYD VDTLDMVFLD HWKDRYLPDT LLLEECGLLR KGTVLLADNV ICPGAPDFLA HVRGSSCFEC THYQSFLEYR EVVDGLEKAI YKGPGSEAGP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Catechol O-methyltransferase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Catechol O-methyltransferase Protein