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Recombinant Human U1 small nuclear ribonucleoprotein 70 kDa Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8429
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 210

Size
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Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8429-ec-10ug
Recombinant Human U1 small nuclear ribonucleoprotein 70 kDa Protein General Information
Alternate Names
U1-70K; Snp1; U170K; SNRP70; U1AP; U1RNP; RPU1; RNPU1Z
Curated Database and Bioinformatic Data
Gene SymbolSNRP70
Entrez Gene ID6625
Ensemble Gene IDENSG00000104852
RefSeq Protein Accession(s)NP_001287998.1
RefSeq mRNA Accession(s)NM_001301069.1, NM_003089.5
UniProt ID(s)P08621
UniGene ID(s)Hs.467097
HGNC ID(s)HGNC:11150
KEGG Gene ID(s)hsa:6625
PharmGKB ID(s)PA35992
General Description of Recombinant Human U1 small nuclear ribonucleoprotein 70 kDa Protein.
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assbly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.

Human U1 small nuclear ribonucleoprotein 70 kDa Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant U1 small nuclear ribonucleoprotein 70 kDa based upon sequence from: Human
Host: QP8429 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) U1 small nuclear ribonucleoprotein 70 kDa, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8429.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - His210
Amino Acid Sequence: MTQFLPPNLL ALFAPRDPIP YLPPLEKLPH EKHHNQPYCG IAPYIREFED PRDAPPPTRA ETREERMERK RREKIERRQQ EVETELKMWD PHNDPNAQGD AFKTLFVARV NYDTTESKLR REFEVYGPIK RIHMVYSKRS GKPRGYAFIE YEHERDMHSA YKHADGKKID GRRVLVDVER GRTVKGWRPR RLGGGLGGTR RGGADVNIRH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human U1 small nuclear ribonucleoprotein 70 kDa Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human U1 small nuclear ribonucleoprotein 70 kDa Protein