enQuire Bio » Products » Recombinant Protein » Recombinant Human Homer protein homolog 1 Protein
Placeholder

Recombinant Human Homer protein homolog 1 Protein

$ 398.00 – $ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8433
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 354

Product NumberDescriptionPrice
QP8433-ec-100ug Size: 100 ug, Tag: His $ 398.00
QP8433-ec-1mg Size: 1 mg, Tag: His $ 1,728.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8433-ec-10ug
Recombinant Human Homer protein homolog 1 Protein General Information
Alternate Names
HOMER; HOMER1B; HOMER1C; HOMER1A; Ves-1; SYN47
Curated Database and Bioinformatic Data
Gene SymbolHOMER1
Entrez Gene ID9456
Ensemble Gene IDENSG00000152413
RefSeq Protein Accession(s)NP_001264006.1
RefSeq mRNA Accession(s)NM_001277077.1, NM_001277078.1, NM_004272.4
UniProt ID(s)Q86YM7
UniGene ID(s)Hs.591761
HGNC ID(s)HGNC:17512
COSMIC ID Link(s)HOMER1
KEGG Gene ID(s)hsa:9456
PharmGKB ID(s)PA134972608
General Description of Recombinant Human Homer protein homolog 1 Protein.
Postsynaptic density scaffolding protein. Binds and cross-links Cytoplasmic domain regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.

Human Homer protein homolog 1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Homer protein homolog 1 based upon sequence from: Human
Host: QP8433 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Homer protein homolog 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8433.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Ser354
Amino Acid Sequence: MGEQPIFSTR AHVFQIDPNT KKNWVPTSKH AVTVSYFYDS TRNVYRIISL DGSKAIINST ITPNMTFTKT SQKFGQWADS RANTVYGLGF SSEHHLSKFA EKFQEFKEAA RLAKEKSQEK MELTSTPSQE SAGGDLQSPL TPESINGTDD ERTPDVTQNS EPRAEPTQNA LPFSHSSAIS KHWEAELATL KGNNAKLTAA LLESTANVKQ WKQQLAAYQE EAERLHKRVT ELECVSSQAN AVHTHKTELN QTIQELEETL KLKEEEIERL KQEIDNAREL QEQRDSLTQK LQEVEIRNKD LEGQLSDLEQ RLEKSQNEQE AFRNNLKTLL EILDGKIFEL TELRDNLAKL LECS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Homer protein homolog 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.

Be the first to review “Recombinant Human Homer protein homolog 1 Protein”

Your email address will not be published. Required fields are marked *

Share a Protocol (View Reviewed Protocols Below)

Protocol Title

Materials

Methods

Notes

  protocol submission gif

Related Products

-
enQuire Bio, LLC   8420 S Continental Divide Rd, #202   Littleton, CO 80127
Chat: See lower right corner. | enquire@enquirebio.com | Fax: 1-720-897-3730
Customer Service Available M-F 8AM-6PM MST or 24/7 Via Email

Recombinant Human Homer protein homolog 1 Protein