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Recombinant Human Polycomb complex protein BMI-1 Protein

$ 398.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8441
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 250

Product NumberDescriptionPrice
QP8441-ec-100ug Size: 100 ug, Tag: GST $ 398.00
QP8441-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8441-ec-10ug
Recombinant Human Polycomb complex protein BMI-1 Protein General Information
Alternate Names
FLVI2/BMI1; PCGF4; RNF51; flvi-2/bmi-1
Curated Database and Bioinformatic Data
Gene SymbolBMI1
Entrez Gene ID100532731
Ensemble Gene IDENSG00000168283
RefSeq Protein Accession(s)NP_001190991.1
RefSeq mRNA Accession(s)NM_001204062.1, NM_005180.8
UniProt ID(s)P35226
UniGene ID(s)Hs.380403
HGNC ID(s)HGNC:1066
COSMIC ID Link(s)BMI1
KEGG Gene ID(s)hsa:100532731
PharmGKB ID(s)PA25376
General Description of Recombinant Human Polycomb complex protein BMI-1 Protein.
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin rodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Human Polycomb complex protein BMI-1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Polycomb complex protein BMI-1 based upon sequence from: Human
Host: QP8441 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Polycomb complex protein BMI-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8441.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - Glu250
Amino Acid Sequence: MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE DKRIITDDEI ISLSIEFFDQ NRLDRKVNKD KEKSKEEVND KRYLRCPAAM TVMHLRKFLR SKMDIPNTFQ IDVMYEEEPL KDYYTLMDIA YIYTWRRNGP LPLKYRVRPT CKRMKISHQR DGLTNAGELE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Polycomb complex protein BMI-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Polycomb complex protein BMI-1 Protein