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Recombinant Human Ras-related GTP-binding protein 1

$ 398.00 – $ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8446
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 247

Product NumberDescriptionPrice
QP8446-ec-100ug Size: 100 ug, Tag: GST $ 398.00
QP8446-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8446-ec-10ug
Recombinant Human Ras-related GTP-binding protein A Protein General Information
Alternate Names
FIP1; FIP-1; RAGA
Curated Database and Bioinformatic Data
Gene SymbolRAGA
Entrez Gene ID10670
Ensemble Gene IDENSG00000155876
RefSeq Protein Accession(s)NP_006561.1
RefSeq mRNA Accession(s)NM_006570.4
UniProt ID(s)Q7L523
UniGene ID(s)Hs.743260
HGNC ID(s)HGNC:16963
KEGG Gene ID(s)hsa:10670
PharmGKB ID(s)PA134980509
General Description of Recombinant Human Ras-related GTP-binding protein A Protein.
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

Human Ras-related GTP-binding protein A Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Ras-related GTP-binding protein A based upon sequence from: Human
Host: QP8446 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Ras-related GTP-binding protein A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8446.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - Ala247
Amino Acid Sequence: MPNTAMKKKV LLMGKSGSGK TSMRSIIFAN YIARDTRRLG ATIDVEHSHV RFLGNLVLNL WDCGGQDTFM ENYFTSQRDN IFRNVEVLIY VFDVESRELE KDMHYYQSCL EAILQNSPDA KIFCLVHKMD LVQEDQRDLI FKEREEDLRR LSRPLECACF RTSIWDETLY KAWSSIVYQL IPNVQQLEMN LRNFAQIIEA DEVLLFERAT FLVISHYQCK EQRDVHRFEK ISNIIKQFKL SCSKLAA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Ras-related GTP-binding protein A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Ras-related GTP-binding protein 1