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Recombinant Human Negative elongation factor B Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8455
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 192

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8455-ec-10ug
Recombinant Human Negative elongation factor B Protein General Information
Alternate Names
NELF-B; COBRA1
Curated Database and Bioinformatic Data
Gene SymbolCOBRA1
Entrez Gene ID25920
Ensemble Gene IDENSG00000188986
RefSeq Protein Accession(s)NP_056271.3
RefSeq mRNA Accession(s)NM_015456.4
UniProt ID(s)Q8WX92
UniGene ID(s)Hs.521809
HGNC ID(s)HGNC:24324
COSMIC ID Link(s)COBRA1
KEGG Gene ID(s)hsa:25920
PharmGKB ID(s)PA162382703
General Description of Recombinant Human Negative elongation factor B Protein.
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.

Human Negative elongation factor B Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Negative elongation factor B based upon sequence from: Human
Host: QP8455 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Negative elongation factor B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8455.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Leu8 - Glu199
Amino Acid Sequence: LGVANGEDLK ETLTNCTEPL KAIEQFQTEN GVLLPSLQSA LPFLDLHGTP RLEFHQSVFD ELRDKLLERV SAIASEGKAE ERYKKLEDLL EKSFSLVKMP SLQPVVMCVM KHLPKVPEKK LKLVMADKEL YRACAVEVKR QIWQDNQALF GDEVSPLLKQ YILEKESALF STELSVLHNF FSPSPKTRRQ GE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Negative elongation factor B Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Negative elongation factor B Protein