PDF DatasheetHuman Anaphase-promoting complex subunit 5 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Anaphase-promoting complex subunit 5 based upon sequence from: Human
Host: QP8491 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Anaphase-promoting complex subunit 5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8491.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ala2 – Thr232
Amino Acid Sequence: ASVHESLYFN PMMTNGVVHA NVFGIKDWVT PYKIAVLVLL NEMSRTGEGA VSLMERRRLN QLLLPLLQGP DITLSKLYKL IEESCPQLAN SVQIRIKLMA EGELKDMEQF FDDLSDSFSG TEPEVHKTSV VGLFLRHMIL AYSKLSFSQV FKLYTALQQY FQNGEKKTVE DADMELTSRD EGERKMEKEE LDVSVREEEV SCSGPLSQKQ AEFFLSQQAS LLKNDETKAL T
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Anaphase-promoting complex subunit 5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Anaphase-promoting complex subunit 5 Protein General Information | |
|---|---|
| Alternate Names | |
| APC5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ANAPC5 |
| Entrez Gene ID | 51433 |
| Ensemble Gene ID | ENSG00000089053 |
| RefSeq Protein Accession(s) | NP_001131031.1 |
| RefSeq mRNA Accession(s) | NM_001137559.1, NM_001330489.1, NM_016237.4 |
| UniProt ID(s) | Q9UJX4 |
| UniGene ID(s) | Hs.7101 |
| HGNC ID(s) | HGNC:15713 |
| COSMIC ID Link(s) | ANAPC5 |
| KEGG Gene ID(s) | hsa:51433 |
| PharmGKB ID(s) | PA24788 |
| General Description of Recombinant Human Anaphase-promoting complex subunit 5 Protein. | |
| Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of ‘Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ‘Lys-48’- and ‘Lys-63’-linked polyubiquitin chains. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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