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Recombinant Human CASP3 / Caspase-3 / CASP-3 Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8509
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 147

Product NumberDescriptionPrice
QP8509-ec-10ug Size: 10 ug, Tag: His $ 148.00
QP8509-ec-50ug Size: 50 ug, Tag: His $ 218.00
QP8509-ec-100ug Size: 100 ug, Tag: His $ 378.00
QP8509-ec-200ug Size: 200 ug, Tag: His $ 628.00
QP8509-ec-500ug Size: 500 ug, Tag: His $ 1,048.00
QP8509-ec-1mg Size: 1 mg, Tag: His $ 1,678.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8509-ec-10ug
Recombinant Human CASP3 / Caspase-3 / CASP-3 Protein General Information
Alternate Names
CASP3; Caspase-3; CASP-3
Curated Database and Bioinformatic Data
Gene SymbolCASP3
Entrez Gene ID836
Ensemble Gene IDENSG00000164305
RefSeq Protein Accession(s)NP_004337.2
RefSeq mRNA Accession(s)NM_004346.3, NM_032991.2, XM_011532301.1
UniProt ID(s)P42574
UniGene ID(s)Hs.141125
HGNC ID(s)HGNC:1504
COSMIC ID Link(s)CASP3
KEGG Gene ID(s)hsa:836
PharmGKB ID(s)PA26087
General Description of Recombinant Human CASP3 / Caspase-3 / CASP-3 Protein.
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory elent binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the mbrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

Human CASP3 / Caspase-3 / CASP-3 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant CASP3 / Caspase-3 / CASP-3 based upon sequence from: Human
Host: QP8509 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CASP3 / Caspase-3 / CASP-3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8509.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser29 - Asp175
Amino Acid Sequence: SGISLDNSYK MDYPEMGLCI IINNKNFHKS TGMTSRSGTD VDAANLRETF RNLKYEVRNK NDLTREEIVE LMRDVSKEDH SKRSSFVCVL LSHGEEGIIF GTNGPVDLKK ITNFFRGDRC RSLTGKPKLF IIQACRGTEL DCGIETD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CASP3 / Caspase-3 / CASP-3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human CASP3 / Caspase-3 / CASP-3 Protein