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Recombinant Human AGRP Protein

$ 148.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8510
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 50

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8510-ec-10ug
Recombinant Human AGRP Protein (83-132aa) General Information
Alternate Names
AGRP; ART; AGRT; ASIP2
Curated Database and Bioinformatic Data
Gene SymbolAGRP
Entrez Gene ID181
Ensemble Gene IDENSG00000159723
RefSeq Protein Accession(s)NP_001129.1
RefSeq mRNA Accession(s)NM_001138.1
UniProt ID(s)O00253
UniGene ID(s)Hs.104633
HGNC ID(s)HGNC:330
COSMIC ID Link(s)AGRP
KEGG Gene ID(s)hsa:181
PharmGKB ID(s)PA24627
General Description of Recombinant Human AGRP Protein (83-132aa).
Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin syst. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R . Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.5 Publications

Human AGRP Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant AGRP based upon sequence from: Human
Host: QP8510 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) AGRP, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8510.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser83 - Thr132
Amino Acid Sequence: SSRRCVRLHE SCLGQQVPCC DPCATCYCRF FNAFCYCRKL GTAMNPCSRT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human AGRP Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human AGRP Protein