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Recombinant Human Angiogenin Protein

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SKU: QP8511
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 122

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On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8511-ec-10ug
Recombinant Human Angiogenin Protein General Information
Alternate Names
RAA1; HEL168; ALS9; RNASE4; RNASE5
Curated Database and Bioinformatic Data
Gene SymbolRNASE5
Entrez Gene ID283
Ensemble Gene IDENSG00000214274
RefSeq Protein Accession(s)NP_001091046.1
RefSeq mRNA Accession(s)NM_001097577.2, NM_001145.4
UniProt ID(s)P03950
UniGene ID(s)Hs.283749
HGNC ID(s)HGNC:483
KEGG Gene ID(s)hsa:283
PharmGKB ID(s)PA24790
General Description of Recombinant Human Angiogenin Protein.
Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.

Human Angiogenin Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Angiogenin based upon sequence from: Human
Host: QP8511 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Angiogenin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8511.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Asp26 - Pro147
Amino Acid Sequence: DNSRYTHFLT QHYDAKPQGR DDRYCESIMR RRGLTSPCKD INTFIHGNKR SIKAICENKN GNPHRENLRI SKSSFQVTTC KLHGGSPWPP CQYRATAGFR NVVVACENGL PVHLDQSIFR RP
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Angiogenin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Angiogenin Protein