SDS-PAGE separation of QP8512 followed by commassie total protein stain results in a primary band consistent with reported data for Angiopoietin-2 / ANG2. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Angiopoietin-2 / ANG2 Protein

$ 98.00 – $ 1,938.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP8512
Species: Human
Available Tags: His
Host: E.coli, Yeast.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 467

Product Number	Description	Price
QP8512-ec-100ug	Size: 100 ug, Tag: His	$ 448.00
QP8512-ec-1mg	Size: 1 mg, Tag: His	$ 1,938.00
QP8512-ye-10ug	Size: 10 ug, Tag: His	$ 98.00
QP8512-ye-50ug	Size: 50 ug, Tag: His	$ 248.00
QP8512-ye-100ug	Size: 100 ug, Tag: His	$ 388.00
QP8512-ye-200ug	Size: 200 ug, Tag: His	$ 638.00
QP8512-ye-500ug	Size: 500 ug, Tag: His	$ 1,108.00
QP8512-ye-1mg	Size: 1 mg, Tag: His	$ 1,818.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP8512-ec-10ug

Recombinant Human Angiopoietin-2 / ANG2 Protein General Information
Alternate Names
Angiopoietin-2; ANG2; Agpt2; Ang2; Ang-2
Curated Database and Bioinformatic Data
Gene Symbol	ANGPT2
Entrez Gene ID	285
Ensemble Gene ID	ENSG00000091879
RefSeq Protein Accession(s)	NP_001112359.1
RefSeq mRNA Accession(s)	NM_001118887.1, NM_001118888.1, NM_001147.2
UniProt ID(s)	O15123
UniGene ID(s)	Hs.583870
HGNC ID(s)	HGNC:485
COSMIC ID Link(s)	ANGPT2
KEGG Gene ID(s)	hsa:285
PharmGKB ID(s)	PA24792
General Description of Recombinant Human Angiopoietin-2 / ANG2 Protein.
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Human Angiopoietin-2 / ANG2 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Angiopoietin-2 / ANG2 based upon sequence from: Human

Host: QP8512 protein expressed in E.coli, Yeast..

Tag: His

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Angiopoietin-2 / ANG2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP8512.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Tyr19 - Lys485

Amino Acid Sequence: YNNFRKSMDS IGKKQYQVQH GSCSYTFLLP EMDNCRSSSS PYVSNAVQRD APLEYDDSVQ RLQVLENIME NNTQWLMKLE NYIQDNMKKE MVEIQQNAVQ NQTAVMIEIG TNLLNQTAEQ TRKLTDVEAQ VLNQTTRLEL QLLEHSLSTN KLEKQILDQT SEINKLQDKN SFLEKKVLAM EDKHIIQLQS IKEEKDQLQV LVSKQNSIIE ELEKKIVTAT VNNSVLQKQQ HDLMETVNNL LTMMSTSNSA KDPTVAKEEQ ISFRDCAEVF KSGHTTNGIY TLTFPNSTEE IKAYCDMEAG GGGWTIIQRR EDGSVDFQRT WKEYKVGFGN PSGEYWLGNE FVSQLTNQQR YVLKIHLKDW EGNEAYSLYE HFYLSSEELN YRIHLKGLTG TAGKISSISQ PGNDFSTKDG DNDKCICKCS QMLTGGWWFD ACGPSNLNGM YYPQRQNTNK FNGIKWYYWK GSGYSLK

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human Angiopoietin-2 / ANG2 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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