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Recombinant Human Caspase-1 Protein

$ 88.00$ 1,618.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8518
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 150

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8518-ec-10ug
Recombinant Human Caspase-1 Protein General Information
Alternate Names
IL1BC; ICE; P45
Curated Database and Bioinformatic Data
Gene SymbolCASP1
Entrez Gene ID834
Ensemble Gene IDENSG00000137752
RefSeq Protein Accession(s)NP_001214.1
RefSeq mRNA Accession(s)NM_001223.4, NM_001257118.2, NM_001257119.2, NM_033292.3, NM_033293.3, NM_033294.3, NM_033295.3
UniProt ID(s)P29466
UniGene ID(s)Hs.2490
HGNC ID(s)HGNC:1499
COSMIC ID Link(s)CASP1
KEGG Gene ID(s)hsa:834
PharmGKB ID(s)PA26083
General Description of Recombinant Human Caspase-1 Protein.
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory elent binding proteins (SREBPs). Can also promote apoptosis.

Human Caspase-1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Caspase-1 based upon sequence from: Human
Host: QP8518 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Caspase-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8518.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asn120 - Asn269
Amino Acid Sequence: NPAMPTSSGS EGNVKLCSLE EAQRIWKQKS AEIYPIMDKS SRTRLALIIC NEEFDSIPRR TGAEVDITGM TMLLQNLGYS VDVKKNLTAS DMTTELEAFA HRPEHKTSDS TFLVFMSHGI REGICGKKHS EQVPDILQLN AIFNMLNTKN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Caspase-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Caspase-1 Protein