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Recombinant Human FAS / CD95 / APO-1 / TNFRSF6 Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8542
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 146

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8542-ec-10ug
Recombinant Human FAS / CD95 / APO-1 / TNFRSF6 Protein General Information
Alternate Names
FAS; CD95; APO-1; TNFRSF6; CD95; FASTM; APO-1; ALPS1A; APT1; FAS1; TNFRSF6
Curated Database and Bioinformatic Data
Gene SymbolFAS
Entrez Gene ID355
Ensemble Gene IDENSG00000026103
RefSeq Protein Accession(s)NP_000034.1
RefSeq mRNA Accession(s)NM_000043.5, NM_001320619.1, NM_152871.3, NM_152872.3
UniProt ID(s)P25445
UniGene ID(s)Hs.244139
HGNC ID(s)HGNC:11920
COSMIC ID Link(s)FAS
KEGG Gene ID(s)hsa:355
PharmGKB ID(s)PA36613
General Description of Recombinant Human FAS / CD95 / APO-1 / TNFRSF6 Protein.
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Human FAS / CD95 / APO-1 / TNFRSF6 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant FAS / CD95 / APO-1 / TNFRSF6 based upon sequence from: Human
Host: QP8542 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) FAS / CD95 / APO-1 / TNFRSF6, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8542.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Gln26 - Arg171
Amino Acid Sequence: QVTDINSKGL ELRKTVTTVE TQNLEGLHHD GQFCHKPCPP GERKARDCTV NGDEPDCVPC QEGKEYTDKA HFSSKCRRCR LCDEGHGLEV EINCTRTQNT KCRCKPNFFC NSTVCEHCDP CTKCEHGIIK ECTLTSNTKC KEEGSR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human FAS / CD95 / APO-1 / TNFRSF6 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human FAS / CD95 / APO-1 / TNFRSF6 Protein