SDS-PAGE separation of QP8563 followed by commassie total protein stain results in a primary band consistent with reported data for SNCA / alpha-Synuclein. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human SNCA / alpha-Synuclein Protein

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SKU: QP8563
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 139

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Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP8563-ec-10ug

Recombinant Human SNCA / alpha-Synuclein Protein General Information
Alternate Names
SNCA; alpha-Synuclein; PD1; NACP; PARK1; PARK4
Curated Database and Bioinformatic Data
Gene Symbol	Snca
Entrez Gene ID	6622
Ensemble Gene ID	ENSG00000145335
RefSeq Protein Accession(s)	NP_000336.1
RefSeq mRNA Accession(s)	NM_000345.3, NM_001146054.1, NM_001146055.1, NM_007308.2, XM_011532208.2, XM_017008562.1, XM_017008563.1
UniProt ID(s)	P37840
UniGene ID(s)	Hs.21374
HGNC ID(s)	HGNC:11138
COSMIC ID Link(s)	SNCA
KEGG Gene ID(s)	hsa:6622
PharmGKB ID(s)	PA35986
General Description of Recombinant Human SNCA / alpha-Synuclein Protein.
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Human SNCA / alpha-Synuclein Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant SNCA / alpha-Synuclein based upon sequence from: Human

Host: QP8563 protein expressed in E. coli.

Tag: GST

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) SNCA / alpha-Synuclein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP8563.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Met1 - Glu139

Amino Acid Sequence: MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPE

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human SNCA / alpha-Synuclein Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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