SDS-PAGE separation of QP8565 followed by commassie total protein stain results in a primary band consistent with reported data for CD54 / ICAM-1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human CD54 / ICAM-1 Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8565
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 453

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8565-ec-10ug
Recombinant Human CD54 / ICAM-1 Protein General Information
Alternate Names
CD54; ICAM-1; CD54; Icam-1; MALA-2; Ly-47
Curated Database and Bioinformatic Data
Gene SymbolICAM1
Entrez Gene ID3383
Ensemble Gene IDENSG00000090339
RefSeq Protein Accession(s)NP_000192.2
RefSeq mRNA Accession(s)NM_000201.2
UniProt ID(s)P05362
UniGene ID(s)Hs.643447
HGNC ID(s)HGNC:5344
COSMIC ID Link(s)ICAM1
KEGG Gene ID(s)hsa:3383
PharmGKB ID(s)PA29592
General Description of Recombinant Human CD54 / ICAM-1 Protein.
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagent promotes the assbly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Human CD54 / ICAM-1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant CD54 / ICAM-1 based upon sequence from: Human
Host: QP8565 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CD54 / ICAM-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8565.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Gln28 - Glu480
Amino Acid Sequence: QTSVSPSKVI LPRGGSVLVT CSTSCDQPKL LGIETPLPKK ELLLPGNNRK VYELSNVQED SQPMCYSNCP DGQSTAKTFL TVYWTPERVE LAPLPSWQPV GKNLTLRCQV EGGAPRANLT VVLLRGEKEL KREPAVGEPA EVTTTVLVRR DHHGANFSCR TELDLRPQGL ELFENTSAPY QLQTFVLPAT PPQLVSPRVL EVDTQGTVVC SLDGLFPVSE AQVHLALGDQ RLNPTVTYGN DSFSAKASVS VTAEDEGTQR LTCAVILGNQ SQETLQTVTI YSFPAPNVIL TKPEVSEGTE VTVKCEAHPR AKVTLNGVPA QPLGPRAQLL LKATPEDNGR SFSCSATLEV AGQLIHKNQT RELRVLYGPR LDERDCPGNW TWPENSQQTP MCQAWGNPLP ELKCLKDGTF PLPIGESVTV TRDLEGTYLC RARSTQGEVT RKVTVNVLSP RYE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CD54 / ICAM-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human CD54 / ICAM-1 Protein