SDS-PAGE separation of QP8566 followed by commassie total protein stain results in a primary band consistent with reported data for TNFR1 / CD120a / TNFRSF1A. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein

$ 148.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8566
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 180

Size
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Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8566-ec-10ug
Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein General Information
Alternate Names
TNFR1; CD120a; TNFRSF1A; TNF-R55; TNF-alphaR1; Tnfr1; p55-R; FPF; TNFRp55; TNF-R; TNF-R-I; TNF-R1; TNFAR; TNFR60; TNFalpha-R1; Tnfr-2; p55; CD120a; TNFRI
Curated Database and Bioinformatic Data
Gene SymbolTNFRSF1A
Entrez Gene ID7132
Ensemble Gene IDENSG00000067182
RefSeq Protein Accession(s)NP_001056.1
RefSeq mRNA Accession(s)NM_001065.3, NM_001346091.1, NM_001346092.1
UniProt ID(s)P19438
UniGene ID(s)Hs.279594
HGNC ID(s)HGNC:11916
COSMIC ID Link(s)TNFRSF1A
KEGG Gene ID(s)hsa:7132
PharmGKB ID(s)PA36609
General Description of Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein.
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Human TNFR1 / CD120a / TNFRSF1A Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant TNFR1 / CD120a / TNFRSF1A based upon sequence from: Human
Host: QP8566 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TNFR1 / CD120a / TNFRSF1A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8566.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Val31 - Thr210
Amino Acid Sequence: VPHLGDREKR DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD CRECESGSFT ASENHLRHCL SCSKCRKEMG QVEISSCTVD RDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE NVKGTEDSGT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TNFR1 / CD120a / TNFRSF1A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein