SDS-PAGE separation of QP8682 followed by commassie total protein stain results in a primary band consistent with reported data for ANGPTL4. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human ANGPTL4 Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8682
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 376

Size
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Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8682-ec-10ug
Recombinant Human ANGPTL4 Protein General Information
Alternate Names
ANGPTL4; NL2; pp1158; HARP; HFARP; TGQTL; UNQ171; ARP4; FIAF; PGAR
Curated Database and Bioinformatic Data
Gene SymbolANGPTL4
Entrez Gene ID51129
Ensemble Gene IDENSG00000167772
RefSeq Protein Accession(s)NP_001034756.1
RefSeq mRNA Accession(s)NM_001039667.2, NM_139314.2
UniProt ID(s)Q9BY76
UniGene ID(s)Hs.9613
HGNC ID(s)HGNC:16039
COSMIC ID Link(s)ANGPTL4
KEGG Gene ID(s)hsa:51129
PharmGKB ID(s)PA24797
General Description of Recombinant Human ANGPTL4 Protein.
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial Extracellular domain matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation .

Human ANGPTL4 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant ANGPTL4 based upon sequence from: Human
Host: QP8682 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) ANGPTL4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8682.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Val28 - Glu403
Amino Acid Sequence: VQSKSPRFAS WDEMNVLAHG LLQLGQGLRE HAERTRSQLS ALERRLSACG SACQGTEGST DLPLAPESRV DPEVLHSLQT QLKAQNSRIQ QLFHKVAQQQ RHLEKQHLRI QHLQSQFGLL DHKHLDHEVA KPARRKRLPE MAQPVDPAHN VSRLHRLPRD CQELFQVGER QSGLFEIQPQ GSPPFLVNCK MTSDGGWTVI QRRHDGSVDF NRPWEAYKAG FGDPHGEFWL GLEKVHSITG DRNSRLAVQL RDWDGNAELL QFSVHLGGED TAYSLQLTAP VAGQLGATTV PPSGLSVPFS TWDQDHDLRR DKNCAKSLSG GWWFGTCSHS NLNGQYFRSI PQQRQKLKKG IFWKTWRGRY YPLQATTMLI QPMAAE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human ANGPTL4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human ANGPTL4 Protein