SDS-PAGE separation of QP8712 followed by commassie total protein stain results in a primary band consistent with reported data for LCAT. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human LCAT Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8712
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 409

Product NumberDescriptionPrice
QP8712-ec-100ug Size: 100 ug, Tag: His $ 448.00
QP8712-ec-1mg Size: 1 mg, Tag: His $ 1,938.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8712-ec-10ug
Recombinant Human LCAT Protein General Information
Alternate Names
LCAT
Curated Database and Bioinformatic Data
Gene SymbolLCAT
Entrez Gene ID3931
Ensemble Gene IDENSG00000213398
RefSeq Protein Accession(s)NP_000220.1
RefSeq mRNA Accession(s)NM_000229.1
UniProt ID(s)P04180
UniGene ID(s)Hs.387239
HGNC ID(s)HGNC:6522
COSMIC ID Link(s)LCAT
KEGG Gene ID(s)hsa:3931
PharmGKB ID(s)PA226
General Description of Recombinant Human LCAT Protein.
Central enzyme in the Extracellular domain metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for rodeling high-density lipoprotein particles into their spherical forms.

Human LCAT Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant LCAT based upon sequence from: Human
Host: QP8712 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) LCAT, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8712.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Phe25 - Ser433
Amino Acid Sequence: FWLLNVLFPP HTTPKAELSN HTRPVILVPG CLGNQLEAKL DKPDVVNWMC YRKTEDFFTI WLDLNMFLPL GVDCWIDNTR VVYNRSSGLV SNAPGVQIRV PGFGKTYSVE YLDSSKLAGY LHTLVQNLVN NGYVRDETVR AAPYDWRLEP GQQEEYYRKL AGLVEEMHAA YGKPVFLIGH SLGCLHLLYF LLRQPQAWKD RFIDGFISLG APWGGSIKPM LVLASGDNQG IPIMSSIKLK EEQRITTTSP WMFPSRMAWP EDHVFISTPS FNYTGRDFQR FFADLHFEEG WYMWLQSRDL LAGLPAPGVE VYCLYGVGLP TPRTYIYDHG FPYTDPVGVL YEDGDDTVAT RSTELCGLWQ GRQPQPVHLL PLHGIQHLNM VFSNLTLEHI NAILLGAYRQ GPPASPTAS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human LCAT Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human LCAT Protein