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Recombinant Human IFNAR2 / IFNABR Protein

$ 88.00$ 1,618.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8715
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 216

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8715-ec-10ug
Recombinant Human IFNAR2 / IFNABR Protein (27-242aa) General Information
Curated Database and Bioinformatic Data
Gene SymbolIFNAR2
Entrez Gene ID3455
Ensemble Gene IDENSG00000159110
RefSeq Protein Accession(s)NP_000865.2
RefSeq mRNA Accession(s)NM_000874.4, NM_001289125.1, NM_001289126.1, NM_001289128.1, NM_207584.2, NM_207585.2
UniProt ID(s)P48551
UniGene ID(s)Hs.708195
HGNC ID(s)HGNC:5433
COSMIC ID Link(s)Ifnar2
KEGG Gene ID(s)hsa:3455
PharmGKB ID(s)PA29671
General Description of Recombinant Human IFNAR2 / IFNABR Protein (27-242aa).
Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.

Human IFNAR2 / IFNABR Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant IFNAR2 / IFNABR based upon sequence from: Human
Host: QP8715 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IFNAR2 / IFNABR, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8715.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Ile27 - Ala242
Amino Acid Sequence: ISYDSPDYTD ESCTFKISLR NFRSILSWEL KNHSIVPTHY TLLYTIMSKP EDLKVVKNCA NTTRSFCDLT DEWRSTHEAY VTVLEGFSGN TTLFSCSHNF WLAIDMSFEP PEFEIVGFTN HINVMVKFPS IVEEELQFDL SLVIEEQSEG IVKKHKPEIK GNMSGNFTYI IDKLIPNTNY CVSVYLEHSD EQAVIKSPLK CTLLPPGQES ESAESA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IFNAR2 / IFNABR Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human IFNAR2 / IFNABR Protein