SDS-PAGE separation of QP8716 followed by commassie total protein stain results in a primary band consistent with reported data for Collagen alpha-1(IV) chain. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Collagen alpha-1(IV) chain Protein

$ 398.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP8716
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 138

Product Number	Description	Price
QP8716-ec-100ug	Size: 100 ug, Tag: GST

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP8716-ec-10ug

Recombinant Human Collagen alpha-1(IV) chain Protein (30-167aa) General Information
Alternate Names
BSVD; RATOR
Curated Database and Bioinformatic Data
Gene Symbol	COL4A1
Entrez Gene ID	1282
Ensemble Gene ID	ENSG00000187498
RefSeq Protein Accession(s)	NP_001290039.1
RefSeq mRNA Accession(s)	NM_001303110.1, NM_001845.5
UniProt ID(s)	P02462
UniGene ID(s)	Hs.17441
HGNC ID(s)	HGNC:2202
COSMIC ID Link(s)	COL4A1
KEGG Gene ID(s)	hsa:1282
PharmGKB ID(s)	PA26717
General Description of Recombinant Human Collagen alpha-1(IV) chain Protein (30-167aa).
Type IV collagen is the major structural component of glomerular basent mbranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.

Human Collagen alpha-1(IV) chain Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Collagen alpha-1(IV) chain based upon sequence from: Human

Host: QP8716 protein expressed in E. coli.

Tag: GST

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Collagen alpha-1(IV) chain, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP8716.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Gly30 - Pro167

Amino Acid Sequence: GCAGSGCGKC DCHGVKGQKG ERGLPGLQGV IGFPGMQGPE GPQGPPGQKG DTGEPGLPGT KGTRGPPGAS GYPGNPGLPG IPGQDGPPGP PGIPGCNGTK GERGPLGPPG LPGFAGNPGP PGLPGMKGDP GEILGHVP

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human Collagen alpha-1(IV) chain Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.