SDS-PAGE separation of QP8720 followed by commassie total protein stain results in a primary band consistent with reported data for Wilm's Tumor 1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Wilm's Tumor 1 Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8720
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 300

Product NumberDescriptionPrice
QP8720-ec-100ug Size: 100 ug, Tag: His $ 448.00
QP8720-ec-1mg Size: 1 mg, Tag: His $ 1,938.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8720-ec-10ug
Recombinant Human Wilm's Tumor 1 Protein General Information
Alternate Names
Wilm's Tumor 1; EWS-WT1; GUD; WIT-2; WT33; AWT1; WAGR; NPHS4
Curated Database and Bioinformatic Data
Gene SymbolWT1
Entrez Gene ID7490
Ensemble Gene IDENSG00000184937
RefSeq Protein Accession(s)NP_000369.3
RefSeq mRNA Accession(s)NM_000378.4, NM_001198551.1, NM_001198552.1, NM_024424.3, NM_024426.4
UniProt ID(s)P19544
UniGene ID(s)Hs.591980
HGNC ID(s)HGNC:12796
COSMIC ID Link(s)WT1
KEGG Gene ID(s)hsa:7490
PharmGKB ID(s)PA37395
General Description of Recombinant Human Wilm's Tumor 1 Protein.
Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital syst. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Human Wilm's Tumor 1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Wilm's Tumor 1 based upon sequence from: Human
Host: QP8720 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Wilm's Tumor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8720.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Gln147 - Gln446
Amino Acid Sequence: QGYSTVTFDG TPSYGHTPSH HAAQFPNHSF KHEDPMGQQG SLGEQQYSVP PPVYGCHTPT DSCTGSQALL LRTPYSSDNL YQMTSQLECM TWNQMNLGAT LKGVAAGSSS SVKWTEGQSN HSTGYESDNH TTPILCGAQY RIHTHGVFRG IQDVRRVPGV APTLVRSASE TSEKRPFMCA YPGCNKRYFK LSHLQMHSRK HTGEKPYQCD FKDCERRFSR SDQLKRHQRR HTGVKPFQCK TCQRKFSRSD HLKTHTRTHT GKTSEKPFSC RWPSCQKKFA RSDELVRHHN MHQRNMTKLQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Wilm's Tumor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Wilm's Tumor 1 Protein