SDS-PAGE separation of QP8726 followed by commassie total protein stain results in a primary band consistent with reported data for Glutamate carboxypeptidase 2. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Glutamate carboxypeptidase 2 Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8726
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 703

Size
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Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8726-ec-10ug
Recombinant Human Glutamate carboxypeptidase 2 Protein General Information
Alternate Names
FOLH; NAALAD1; NAALAdase; PSMA; GCPII; FGCP; GCP2; PSM; mGCP
Curated Database and Bioinformatic Data
Gene SymbolFOLH
Entrez Gene ID2346
Ensemble Gene IDENSG00000086205
RefSeq Protein Accession(s)NP_001014986.1
RefSeq mRNA Accession(s)NM_001014986.1, NM_001193471.1, NM_001193472.1, NM_001193473.1, NM_004476.1, XM_017017434.1, XM_017017435.1, XM_017017436.1, XM_017017437.1, XM_017017442.1, XM_017017443.1, XM_017017444.1, XM_017017445.1, XM_017017446.1, XM_017017447.1, XM_017017448.1
UniProt ID(s)Q04609
UniGene ID(s)Hs.551896
HGNC ID(s)HGNC:3788
KEGG Gene ID(s)hsa:2346
PharmGKB ID(s)PA28205
General Description of Recombinant Human Glutamate carboxypeptidase 2 Protein.
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression.Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

Human Glutamate carboxypeptidase 2 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Glutamate carboxypeptidase 2 based upon sequence from: Human
Host: QP8726 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Glutamate carboxypeptidase 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8726.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Glu48 - Ala750
Amino Acid Sequence: EATNITPKHN MKAFLDELKA ENIKKFLYNF TQIPHLAGTE QNFQLAKQIQ SQWKEFGLDS VELAHYDVLL SYPNKTHPNY ISIINEDGNE IFNTSLFEPP PPGYENVSDI VPPFSAFSPQ GMPEGDLVYV NYARTEDFFK LERDMKINCS GKIVIARYGK VFRGNKVKNA QLAGAKGVIL YSDPADYFAP GVKSYPDGWN LPGGGVQRGN ILNLNGAGDP LTPGYPANEY AYRRGIAEAV GLPSIPVHPI GYYDAQKLLE KMGGSAPPDS SWRGSLKVPY NVGPGFTGNF STQKVKMHIH STNEVTRIYN VIGTLRGAVE PDRYVILGGH RDSWVFGGID PQSGAAVVHE IVRSFGTLKK EGWRPRRTIL FASWDAEEFG LLGSTEWAEE NSRLLQERGV AYINADSSIE GNYTLRVDCT PLMYSLVHNL TKELKSPDEG FEGKSLYESW TKKSPSPEFS GMPRISKLGS GNDFEVFFQR LGIASGRARY TKNWETNKFS GYPLYHSVYE TYELVEKFYD PMFKYHLTVA QVRGGMVFEL ANSIVLPFDC RDYAVVLRKY ADKIYSISMK HPQEMKTYSV SFDSLFSAVK NFTEIASKFS ERLQDFDKSN PIVLRMMNDQ LMFLERAFID PLGLPDRPFY RHVIYAPSSH NKYAGESFPG IYDALFDIES KVDPSKAWGE VKRQIYVAAF TVQAAAETLS EVA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Glutamate carboxypeptidase 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Glutamate carboxypeptidase 2 Protein