enQuire Bio » Products » Recombinant Protein » Recombinant Human Collagen alpha-2(IV) chain Protein
SDS-PAGE separation of QP8734 followed by commassie total protein stain results in a primary band consistent with reported data for Collagen alpha-2(IV) chain. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP8734 followed by commassie total protein stain results in a primary band consistent with reported data for Collagen alpha-2(IV) chain. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Collagen alpha-2(IV) chain Protein

Please Select Product Options Below To View The Catalog Number.

SKU: QP8734
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 220

Product NumberDescriptionPrice
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8734-ec-10ug
Recombinant Human Collagen alpha-2(IV) chain Protein General Information
Alternate Names
POREN2; ICH
Curated Database and Bioinformatic Data
Gene SymbolCOL4A2
Entrez Gene ID1284
Ensemble Gene IDENSG00000134871
RefSeq Protein Accession(s)NP_001837.2
RefSeq mRNA Accession(s)NM_001846.3
UniProt ID(s)P08572
UniGene ID(s)Hs.508716
HGNC ID(s)HGNC:2203
COSMIC ID Link(s)COL4A2
KEGG Gene ID(s)hsa:1284
PharmGKB ID(s)PA26718
General Description of Recombinant Human Collagen alpha-2(IV) chain Protein.
Type IV collagen is the major structural component of glomerular basent mbranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial mbrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.

Human Collagen alpha-2(IV) chain Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Collagen alpha-2(IV) chain based upon sequence from: Human
Host: QP8734 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Collagen alpha-2(IV) chain, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8734.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Val1493 - Leu1712
Amino Acid Sequence: VKHSQTDQEP MCPVGMNKLW SGYSLLYFEG QEKAHNQDLG LAGSCLARFS TMPFLYCNPG DVCYYASRND KSYWLSTTAP LPMMPVAEDE IKPYISRCSV CEAPAIAIAV HSQDVSIPHC PAGWRSLWIG YSFLMHTAAG DEGGGQSLVS PGSCLEDFRA TPFIECNGGR GTCHYYANKY SFWLTTIPEQ SFQGSPSADT LKAGLIRTHI SRCQVCMKNL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Collagen alpha-2(IV) chain Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.

Be the first to review “Recombinant Human Collagen alpha-2(IV) chain Protein”

Your email address will not be published. Required fields are marked *

Share a Protocol (View Reviewed Protocols Below)

Protocol Title

Materials

Methods

Notes

  protocol submission gif

Related Products

    -
    enQuire Bio, LLC   8420 S Continental Divide Rd, #202   Littleton, CO 80127
    Chat: See lower right corner. | enquire@enquirebio.com | Fax: 1-720-897-3730
    Customer Service Available M-F 8AM-6PM MST or 24/7 Via Email

    Recombinant Human Collagen alpha-2(IV) chain Protein

    https://enquirebio.com/wp-content/uploads/2018/01/QP8734-Human-Collagen-alpha-2IV-chain-1.jpg