PDF DatasheetHuman TNFAIP8 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant TNFAIP8 based upon sequence from: Human
Host: QP8735 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TNFAIP8, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8735.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: His2 – Ile198
Amino Acid Sequence: HSEAEESKEV ATDVFNSKNL AVQAQKKILG KMVSKSIATT LIDDTSSEVL DELYRVTREY TQNKKEAEKI IKNLIKTVIK LAILYRNNQF NQDELALMEK FKKKVHQLAM TVVSFHQVDY TFDRNVLSRL LNECREMLHQ IIQRHLTAKS HGRVNNVFDH FSDCEFLAAL YNPFGNFKPH LQKLCDGINK MLDEENI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TNFAIP8 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TNFAIP8 Protein General Information | |
|---|---|
| Alternate Names | |
| TNFAIP8; MDC-3.13; NDED; SCCS2; GG2-1; SCC-S2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFAIP8 |
| Entrez Gene ID | 25816 |
| Ensemble Gene ID | ENSG00000145779 |
| RefSeq Protein Accession(s) | NP_001071122.1 |
| RefSeq mRNA Accession(s) | NM_001077654.2, NM_001286813.1, NM_001286814.1, NM_001286815.1, NM_001286817.1, NM_014350.3 |
| UniProt ID(s) | O95379 |
| UniGene ID(s) | Hs.618488 |
| HGNC ID(s) | HGNC:17260 |
| COSMIC ID Link(s) | TNFAIP8 |
| KEGG Gene ID(s) | hsa:25816 |
| PharmGKB ID(s) | PA134957136 |
| General Description of Recombinant Human TNFAIP8 Protein. | |
| Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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