SDS-PAGE separation of QP8751 followed by commassie total protein stain results in a primary band consistent with reported data for B7-H4 / B7S1 / B7x. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human B7-H4 / B7S1 / B7x Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8751
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 233

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8751-ec-10ug
Recombinant Human B7-H4 / B7S1 / B7x Protein General Information
Alternate Names
B7-H4; B7S1; B7x; B7X; PRO1291; B7-H4; B7S1; VCTN1; B7H4; B7h.5
Curated Database and Bioinformatic Data
Gene SymbolVTCN1
Entrez Gene ID79679
Ensemble Gene IDENSG00000134258
RefSeq Protein Accession(s)NP_001240778.1
RefSeq mRNA Accession(s)NM_001253849.1, NM_001253850.1, NM_024626.3
UniProt ID(s)Q7Z7D3
UniGene ID(s)Hs.546434
HGNC ID(s)HGNC:28873
COSMIC ID Link(s)VTCN1
KEGG Gene ID(s)hsa:79679
PharmGKB ID(s)PA142670611
General Description of Recombinant Human B7-H4 / B7S1 / B7x Protein.
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

Human B7-H4 / B7S1 / B7x Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant B7-H4 / B7S1 / B7x based upon sequence from: Human
Host: QP8751 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) B7-H4 / B7S1 / B7x, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8751.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ile26 - Ala258
Amino Acid Sequence: IIGFGISGRH SITVTTVASA GNIGEDGILS CTFEPDIKLS DIVIQWLKEG VLGLVHEFKE GKDELSEQDE MFRGRTAVFA DQVIVGNASL RLKNVQLTDA GTYKCYIITS KGKGNANLEY KTGAFSMPEV NVDYNASSET LRCEAPRWFP QPTVVWASQV DQGANFSEVS NTSFELNSEN VTMKVVSVLY NVTINNTYSC MIENDIAKAT GDIKVTESEI KRRSHLQLLN SKA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human B7-H4 / B7S1 / B7x Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human B7-H4 / B7S1 / B7x Protein