PDF DatasheetHuman VCL / Vinculin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant VCL / Vinculin based upon sequence from: Human
Host: QP8773 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) VCL / Vinculin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8773.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Pro2 – Glu235
Amino Acid Sequence: PVFHTRTIES ILEPVAQQIS HLVIMHEEGE VDGKAIPDLT APVAAVQAAV SNLVRVGKET VQTTEDQILK RDMPPAFIKV ENACTKLVQA AQMLQSDPYS VPARDYLIDG SRGILSGTSD LLLTFDEAEV RKIIRVCKGI LEYLTVAEVV ETMEDLVTYT KNLGPGMTKM AKMIDERQQE LTHQEHRVML VNSMNTVKEL LPVLISAMKI FVTTKNSKNQ GIEEALKNRN FTVE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human VCL / Vinculin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human VCL / Vinculin Protein General Information | |
|---|---|
| Alternate Names | |
| VCL; Vinculin; AA571387; AW545629; 9430097D22; AI462105 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | VCL |
| Entrez Gene ID | 7414 |
| Ensemble Gene ID | ENSG00000035403 |
| RefSeq Protein Accession(s) | NP_003364.1 |
| RefSeq mRNA Accession(s) | NM_003373.3, NM_014000.2 |
| UniProt ID(s) | P18206 |
| UniGene ID(s) | Hs.643896 |
| HGNC ID(s) | HGNC:12665 |
| COSMIC ID Link(s) | VCL |
| KEGG Gene ID(s) | hsa:7414 |
| PharmGKB ID(s) | PA37288 |
| General Description of Recombinant Human VCL / Vinculin Protein. | |
| Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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