SDS-PAGE separation of QP8781 followed by commassie total protein stain results in a primary band consistent with reported data for Carbonyl reductase [NADPH] 1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Carbonyl reductase [NADPH] 1 Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8781
Species: Human
Available Tags: His
Host: E.coli, Yeast.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 276

Product NumberDescriptionPrice
QP8781-ec-10ug Size: 10 ug, Tag: His $ 168.00
QP8781-ec-50ug Size: 50 ug, Tag: His $ 248.00
QP8781-ec-100ug Size: 100 ug, Tag: His $ 428.00
QP8781-ec-200ug Size: 200 ug, Tag: His $ 708.00
QP8781-ec-500ug Size: 500 ug, Tag: His $ 1,178.00
QP8781-ec-1mg Size: 1 mg, Tag: His $ 1,878.00
QP8781-ye-100ug Size: 100 ug, Tag: His $ 528.00
QP8781-ye-500ug Size: 500 ug, Tag: His $ 1,458.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8781-ec-10ug
Recombinant Human Carbonyl reductase Protein 1 Protein General Information
Alternate Names
SDR21C1; hCBR1; CBR
Curated Database and Bioinformatic Data
Gene SymbolCBR1
Entrez Gene ID873
Ensemble Gene IDENSG00000159228
RefSeq Protein Accession(s)NP_001273718.1
RefSeq mRNA Accession(s)NM_001286789.1, NM_001757.3
UniProt ID(s)P16152
UniGene ID(s)Hs.88778
HGNC ID(s)HGNC:1548
COSMIC ID Link(s)CBR1
KEGG Gene ID(s)hsa:873
PharmGKB ID(s)PA26121
General Description of Recombinant Human Carbonyl reductase Protein 1 Protein.
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.

Human Carbonyl reductase [NADPH] 1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Carbonyl reductase [NADPH] 1 based upon sequence from: Human
Host: QP8781 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Carbonyl reductase [NADPH] 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8781.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ser2 - Trp277
Amino Acid Sequence: SSGIHVALVT GGNKGIGLAI VRDLCRLFSG DVVLTARDVT RGQAAVQQLQ AEGLSPRFHQ LDIDDLQSIR ALRDFLRKEY GGLDVLVNNA GIAFKVADPT PFHIQAEVTM KTNFFGTRDV CTELLPLIKP QGRVVNVSSI MSVRALKSCS PELQQKFRSE TITEEELVGL MNKFVEDTKK GVHQKEGWPS SAYGVTKIGV TVLSRIHARK LSEQRKGDKI LLNACCPGWV RTDMAGPKAT KSPEEGAETP VYLALLPPDA EGPHGQFVSE KRVEQW
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Carbonyl reductase [NADPH] 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Carbonyl reductase [NADPH] 1 Protein