SDS-PAGE separation of QP8790 followed by commassie total protein stain results in a primary band consistent with reported data for Plexin-A1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Plexin-A1 Protein

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SKU: QP8790
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 265

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Datasheets and Documentation
Product Datasheet
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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8790-ec-10ug
Recombinant Human Plexin-A1 Protein General Information
Alternate Names
PLEXIN-A1; PLXN1; NOV; NOVP
Curated Database and Bioinformatic Data
Gene SymbolPLXNA1
Entrez Gene ID5361
Ensemble Gene IDENSG00000114554
RefSeq Protein Accession(s)NP_115618.3
RefSeq mRNA Accession(s)NM_032242.3
UniProt ID(s)Q9UIW2
UniGene ID(s)Hs.432329
HGNC ID(s)HGNC:9099
COSMIC ID Link(s)PLXNA1
KEGG Gene ID(s)hsa:5361
General Description of Recombinant Human Plexin-A1 Protein.
Coreceptor for SA3A, SA3C, SA3F and SA6D. Necessary for signaling by class 3 saphorins and subsequent rodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 saphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific saphorins, and its Cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm .

Human Plexin-A1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Plexin-A1 based upon sequence from: Human
Host: QP8790 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Plexin-A1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8790.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Arg32 - Val296
Amino Acid Sequence: RAGGGSQPPF RTFSASDWGL THLVVHEQTG EVYVGAVNRI YKLSGNLTLL RAHVTGPVED NEKCYPPPSV QSCPHGLGST DNVNKLLLLD YAANRLLACG SASQGICQFL RLDDLFKLGE PHHRKEHYLS SVQEAGSMAG VLIAGPPGQG QAKLFVGTPI DGKSEYFPTL SSRRLMANEE DADMFGFVYQ DEFVSSQLKI PSDTLSKFPA FDIYYVYSFR SEQFVYYLTL QLDTQLTSPD AAGEHFFTSK IVRLCVDDPK FYSYV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Plexin-A1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Plexin-A1 Protein