SEQUEST analysis of LC MS/MS spectra obtained from a run with QP8823 identified a match between this protein and the spectra of a peptide sequence that matches a region of Titin.
SEQUEST analysis of LC MS/MS spectra obtained from a run with QP8823 identified a match between this protein and the spectra of a peptide sequence that matches a region of Titin.Additional SEQUEST analysis of the LC MS/MS spectra from QP8823 identified an additional between this protein and the spectra of another peptide sequence that matches a region of Titin confirming successful recombinant synthesis.SDS-PAGE separation of QP8823 followed by commassie total protein stain results in a primary band consistent with reported data for Titin. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Titin Protein

$ 478.00$ 2,058.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8823
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 207

Product NumberDescriptionPrice
QP8823-ec-100ug Size: 100 ug, Tag: His $ 538.00
QP8823-ec-1mg Size: 1 mg, Tag: His $ 2,308.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8823-ec-10ug
Recombinant Human Titin Protein General Information
Alternate Names
MYLK5; CMH9; CMPD4; CMD1G; TMD; EOMFC; LGMD2J; HMERF
Curated Database and Bioinformatic Data
Gene SymbolTTN
Entrez Gene ID7273
Ensemble Gene IDENSG00000155657
RefSeq Protein Accession(s)NP_001243779.1
RefSeq mRNA Accession(s)NM_001256850.1, NM_003319.4, NM_133378.4, NM_133379.4, NM_133432.3
UniProt ID(s)Q8WZ42
UniGene ID(s)Hs.134602
HGNC ID(s)HGNC:12403
KEGG Gene ID(s)hsa:7273
PharmGKB ID(s)PA37067
General Description of Recombinant Human Titin Protein.
Key component in the assbly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, ses to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.

Human Titin Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Titin based upon sequence from: Human
Host: QP8823 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Titin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8823.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Val5398 - Phe5604
Amino Acid Sequence: VGSSICSARV TLREPPSFIK KIESTSSLRG GTAAFQATLK GSLPITVTWL KDSDEITEDD NIRMTFENNV ASLYLSGIEV KHDGKYVCQA KNDAGIQRCS ALLSVKEPAT ITEEAVSIDV TQGDPATLQV KFSGTKEITA KWFKDGQELT LGSKYKISVT DTVSILKIIS TEKKDSGEYT FEVQNDVGRS SCKARINVLD LIIPPSF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Titin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Titin Protein

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