SDS-PAGE separation of QP8855 followed by commassie total protein stain results in a primary band consistent with reported data for NR2C2. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human NR2C2 Protein

$ 448.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8855
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 590

Product NumberDescriptionPrice
QP8855-ec-100ug Size: 100 ug, Tag: His
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8855-ec-10ug
Recombinant Human NR2C2 Protein General Information
Alternate Names
mKIAA4145; TAK1; Tr4; Nuclear receptor subfamily 2 group C member
Curated Database and Bioinformatic Data
Gene SymbolNR2C2
Entrez Gene ID22026
Ensemble Gene IDENSMUSG00000005893
RefSeq Protein Accession(s)NP_001334271.1
RefSeq mRNA Accession(s)NM_001347342.1, NM_011630.3, XM_006505904.3, XM_006505905.3, XM_006505906.3
UniProt ID(s)P49117
UniGene ID(s)Mm.442385
COSMIC ID Link(s)NR2C2
KEGG Gene ID(s)mmu:22026
General Description of Recombinant Human NR2C2 Protein.
Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear recptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during expression during the late phase of spermatogenesis. Activates transcriptional activity of LHCG and is antagonist of PPARA-mediated transactivation . Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses bryonic and fetal globin transcription including that of GATA1. Binds to hormone response elents (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early bryonic development and bryonic st cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior

Human NR2C2 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant NR2C2 based upon sequence from: Human
Host: QP8855 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) NR2C2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8855.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser3 - Thr592
Amino Acid Sequence: SPSPRIQIIS TDSAVASPQR IQIVTDQQTG QKIQIVTAVD ASGSSKQQFI LTSPDGAGTG KVILASPETS SAKQLIFTTS DNLVPGRIQI VTDSASVERL LGKADVQRPQ VVEYCVVCGD KASGRHYGAV SCEGCKGFFK RSVRKNLTYS CRSSQDCIIN KHHRNRCQFC RLKKCLEMGM KMESVQSERK PFDVQREKPS NCAASTEKIY IRKDLRSPLI ATPTFVADKD GARQTGLLDP GMLVNIQQPL IREDGTVLLA ADSKAETSQG ALGTLANVVT SLANLSESLN NGDASEMQPE DQSASEITRA FDTLAKALNT TDSASPPSLA DGIDASGGGS IHVISRDQST PIIEVEGPLL SDTHVTFKLT MPSPMPEYLN VHYICESASR LLFLSMHWAR SIPAFQALGQ DCNTSLVRAC WNELFTLGLA QCAQVMSLST ILAAIVNHLQ NSIQEDKLSG DRIKQVMEHI WKLQEFCNSM AKLDIDGYEY AYLKAIVLFS PDHPGLTGTS QIEKFQEKAQ MELQDYVQKT YSEDTYRLAR ILVRLPALRL MSSNITEELF FTGLIGNVSI DSIIPYILKM ETAEYNGQIT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human NR2C2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.

Be the first to review “Recombinant Human NR2C2 Protein”

Your email address will not be published.

Share a Protocol (View Reviewed Protocols Below)

Protocol Title

Materials

Methods

Notes


  protocol submission gif
enQuire Bio, LLC   8420 S Continental Divide Rd, #202   Littleton, CO 80127
Chat: See lower right corner. | enquire@enquirebio.com | Fax: 1-720-897-3730
Customer Service Available M-F 8AM-6PM MST or 24/7 Via Email

Recombinant Human NR2C2 Protein