SEQUEST analysis of LC MS/MS spectra obtained from a run with QP8867 identified a match between this protein and the spectra of a peptide sequence that matches a region of Transcription factor PU.1.
SEQUEST analysis of LC MS/MS spectra obtained from a run with QP8867 identified a match between this protein and the spectra of a peptide sequence that matches a region of Transcription factor PU.1.Additional SEQUEST analysis of the LC MS/MS spectra from QP8867 identified an additional between this protein and the spectra of another peptide sequence that matches a region of Transcription factor PU.1 confirming successful recombinant synthesis.

Recombinant Human Transcription factor PU.1 Protein

$ 88.00$ 1,618.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8867
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 270

Product NumberDescriptionPrice
QP8867-ec-10ug Size: 10 ug, Tag: His $ 98.00
QP8867-ec-50ug Size: 50 ug, Tag: His $ 248.00
QP8867-ec-100ug Size: 100 ug, Tag: His $ 388.00
QP8867-ec-200ug Size: 200 ug, Tag: His $ 638.00
QP8867-ec-500ug Size: 500 ug, Tag: His $ 1,108.00
QP8867-ec-1mg Size: 1 mg, Tag: His $ 1,818.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8867-ec-10ug
Recombinant Human Transcription factor PU.1 Protein General Information
Alternate Names
OF; PU.1; SPI-A; SFPI1; SPI-1
Curated Database and Bioinformatic Data
Gene SymbolSPI1
Entrez Gene ID6688
Ensemble Gene IDENSG00000066336
RefSeq Protein Accession(s)NP_001074016.1
RefSeq mRNA Accession(s)NM_001080547.1, NM_003120.2
UniProt ID(s)P17947
UniGene ID(s)Hs.502511
HGNC ID(s)HGNC:11241
COSMIC ID Link(s)SPI1
KEGG Gene ID(s)hsa:6688
PharmGKB ID(s)PA36071
General Description of Recombinant Human Transcription factor PU.1 Protein.
Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing .

Human Transcription factor PU.1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Transcription factor PU.1 based upon sequence from: Human
Host: QP8867 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Transcription factor PU.1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8867.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - His270
Amino Acid Sequence: MLQACKMEGF PLVPPPSEDL VPYDTDLYQR QTHEYYPYLS SDGESHSDHY WDFHPHHVHS EFESFAENNF TELQSVQPPQ LQQLYRHMEL EQMHVLDTPM VPPHPSLGHQ VSYLPRMCLQ YPSLSPAQPS SDEEEGERQS PPLEVSDGEA DGLEPGPGLL PGETGSKKKI RLYQFLLDLL RSGDMKDSIW WVDKDKGTFQ FSSKHKEALA HRWGIQKGNR KKMTYQKMAR ALRNYGKTGE VKKVKKKLTY QFSGEVLGRG GLAERRHPPH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Transcription factor PU.1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Transcription factor PU.1 Protein

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