SDS-PAGE separation of QP8877 followed by commassie total protein stain results in a primary band consistent with reported data for CD106 / VCAM1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Rat CD106 / VCAM1 Protein

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SKU: QP8877
Species: Rat
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 667

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Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP8877-ec-10ug

Recombinant Rat CD106 / VCAM1 Protein General Information
Curated Database and Bioinformatic Data
Gene Symbol	VCAM1
Entrez Gene ID	25361
Ensemble Gene ID	ENSRNOG00000014333
RefSeq Protein Accession(s)	NP_037021.1
RefSeq mRNA Accession(s)	NM_012889.1
UniProt ID(s)	P29534
UniGene ID(s)	Rn.11267
COSMIC ID Link(s)	VCAM1
KEGG Gene ID(s)	rno:25361
General Description of Recombinant Rat CD106 / VCAM1 Protein.
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte igration to sites of inflammation.

Rat CD106 / VCAM1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant CD106 / VCAM1 based upon sequence from: Rat

Host: QP8877 protein expressed in E. coli.

Tag: His

Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) CD106 / VCAM1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP8877.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Pro31 - Pro697

Amino Acid Sequence: PEYKTLAQIG DSMLLTCSTT GCESPSFSWR TQIDSPLNGK VKTEGAKSVL TMDPVSFENE HSYLCTATCN SGKLERGIQV DIYSFPKDPE IQFSGPLEVG KPVMVKCLAP DVYPIDRLEI ELFKGDRLMK KQDFVDEMAK KSLETKSLEV IFTPVIEDIE KALVCRAKLY IDQTDSIPKE RETVRELQVY TSPKNTEISV HPSTRLHEGA AVTMTCASEG LPAPEIFWSK KLDNGVLQLL SGNATLTLIA MRMEDSGIYV CEGVNLVGRD KTEVELIVQE KPFTVDISPG SQVAAQVGDS VVLTCAAVGC DSPSFSWRTQ TDSPLNGEVR DEGATSTLTL SPVGVEDEHS YLCTVTCQRR KLEKTIQVEV YSFPEDPEIE ISGPLVHGRP VTVNCTVPNV YPFDHLEIEL LKGETTLLNK FLREEIGTKS LETKSLEMTF IPTAEDTGKA LVCLAKLHSS QMESEPKQRQ STQTLYVNVA PKEPTIWVSP SPVPEEGSPV NLTCSSDGFP TPKILWSRQL KNGELQPLSQ NTTLSFMATK MEDSGIYVCE GINEAGISKK SVELIIQGSS KDIQLTVFPS KSVKEGDTVI ISCTCGSVPE IWIILKKKAK TGDMVLKSVN GSYTIRKAQL QDAGVYECES KTEVGSQLRS LTLDVKGKEN NKDYFSP

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Rat CD106 / VCAM1 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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