SDS-PAGE separation of QP8884 followed by commassie total protein stain results in a primary band consistent with reported data for Angiopoietin-2 / ANG2. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Mouse Angiopoietin-2 / ANG2 Protein

$ 228.00$ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8884
Species: Mouse
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 465

Product NumberDescriptionPrice
QP8884-ec-10ug Size: 10 ug, Tag: His $ 228.00
QP8884-ec-100ug Size: 100 ug, Tag: His $ 578.00
QP8884-ec-1mg Size: 1 mg, Tag: His $ 2,468.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8884-ec-10ug
Recombinant Mouse Angiopoietin-2 / ANG2 Protein General Information
Curated Database and Bioinformatic Data
Gene SymbolAngpt2
Entrez Gene ID11601
Ensemble Gene IDENSMUSG00000031465
RefSeq Protein Accession(s)NP_031452.2
RefSeq mRNA Accession(s)NM_007426.4
UniProt ID(s)O35608
UniGene ID(s)Mm.439874
COSMIC ID Link(s)Angpt2
KEGG Gene ID(s)mmu:11601
General Description of Recombinant Mouse Angiopoietin-2 / ANG2 Protein.
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal .

Mouse Angiopoietin-2 / ANG2 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Angiopoietin-2 / ANG2 based upon sequence from: Mouse
Host: QP8884 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Angiopoietin-2 / ANG2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8884.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Tyr19 - Ser483
Amino Acid Sequence: YSNFRKSVDS TGRRQYQVQN GPCSYTFLLP ETDSCRSSSS PYMSNAVQRD APLDYDDSVQ RLQVLENILE NNTQWLMKLE NYIQDNMKKE MVEIQQNVVQ NQTAVMIEIG TSLLNQTAAQ TRKLTDVEAQ VLNQTTRLEL QLLQHSISTN KLEKQILDQT SEINKLQNKN SFLEQKVLDM EGKHSEQLQS MKEQKDELQV LVSKQSSVID ELEKKLVTAT VNNSLLQKQQ HDLMETVNSL LTMMSSPNSK SSVAIRKEEQ TTFRDCAEIF KSGLTTSGIY TLTFPNSTEE IKAYCDMDVG GGGWTVIQHR EDGSVDFQRT WKEYKEGFGS PLGEYWLGNE FVSQLTGQHR YVLKIQLKDW EGNEAHSLYD HFYLAGEESN YRIHLTGLTG TAGKISSISQ PGSDFSTKDS DNDKCICKCS QMLSGGWWFD ACGPSNLNGQ YYPQKQNTNK FNGIKWYYWK GSGYS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse Angiopoietin-2 / ANG2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Mouse Angiopoietin-2 / ANG2 Protein