PDF DatasheetHuman ASGPR1 / ASGR1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant ASGPR1 / ASGR1 based upon sequence from: Human
Host: QP8899 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) ASGPR1 / ASGR1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8899.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Glu68 – Leu291
Amino Acid Sequence: EELRGLRETF SNFTASTEAQ VKGLSTQGGN VGRKMKSLES QLEKQQKDLS EDHSSLLLHV KQFVSDLRSL SCQMAALQGN GSERTCCPVN WVEHERSCYW FSRSGKAWAD ADNYCRLEDA HLVVVTSWEE QKFVQHHIGP VNTWMGLHDQ NGPWKWVDGT DYETGFKNWR PEQPDDWYGH GLGGGEDCAH FTDDGRWNDD VCQRPYRWVC ETELDKASQE PPLL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human ASGPR1 / ASGR1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human ASGPR1 / ASGR1 Protein General Information | |
|---|---|
| Alternate Names | |
| ASGPR1; ASGR1; Asgr-1; Asgr; ASGPR1; HL-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ASGR1 |
| Entrez Gene ID | 432 |
| Ensemble Gene ID | ENSG00000141505 |
| RefSeq Protein Accession(s) | NP_001184145.1 |
| RefSeq mRNA Accession(s) | NM_001197216.2, NM_001671.4, XM_011523861.2 |
| UniProt ID(s) | P07306 |
| UniGene ID(s) | Hs.12056 |
| HGNC ID(s) | HGNC:742 |
| COSMIC ID Link(s) | ASGR1 |
| KEGG Gene ID(s) | hsa:432 |
| PharmGKB ID(s) | PA25042 |
| General Description of Recombinant Human ASGPR1 / ASGR1 Protein. | |
| Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been roved. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell mbrane surface. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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