SEQUEST analysis of LC MS/MS spectra obtained from a run with QP8905 identified a match between this protein and the spectra of a peptide sequence that matches a region of Histone acetyltransferase KAT5.
SEQUEST analysis of LC MS/MS spectra obtained from a run with QP8905 identified a match between this protein and the spectra of a peptide sequence that matches a region of Histone acetyltransferase KAT5.Additional SEQUEST analysis of the LC MS/MS spectra from QP8905 identified an additional between this protein and the spectra of another peptide sequence that matches a region of Histone acetyltransferase KAT5 confirming successful recombinant synthesis.

Recombinant Human Histone acetyltransferase KAT5 Protein

$ 158.00$ 658.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8905
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 511

Product NumberDescriptionPrice
QP8905-ec-10ug Size: 10 ug, Tag: His $ 158.00
QP8905-ec-200ug Size: 200 ug, Tag: His $ 658.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8905-ec-10ug
Recombinant Human Histone acetyltransferase KAT5 Protein General Information
Alternate Names
HTATIP; cPLA2; TIP; ESA1; HTATIP1; PLIP; TIP60; ZC2HC5
Curated Database and Bioinformatic Data
Gene SymbolKAT5
Entrez Gene ID10524
Ensemble Gene IDENSG00000172977
RefSeq Protein Accession(s)NP_001193762.1
RefSeq mRNA Accession(s)NM_001206833.1, NM_006388.3, NM_182709.2, NM_182710.2
UniProt ID(s)Q92993
UniGene ID(s)Hs.397010
HGNC ID(s)HGNC:5275
COSMIC ID Link(s)KAT5
KEGG Gene ID(s)hsa:10524
PharmGKB ID(s)PA162392746
General Description of Recombinant Human Histone acetyltransferase KAT5 Protein.
Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Component of a SWR1-like complex that specifically mediates the roval of histone H2A.Z/H2AFZ from the nucleosome. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. Relieves NR1D2-mediated inhibition of APOC3 expression by acetylating NR1D2. Promotes FOXP3 acetylation and positively regulates its transcriptional repressor activity

Human Histone acetyltransferase KAT5 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Histone acetyltransferase KAT5 based upon sequence from: Human
Host: QP8905 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Histone acetyltransferase KAT5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8905.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Glu3 - Trp513
Amino Acid Sequence: EVGEIIEGCR LPVLRRNQDN EDEWPLAEIL SVKDISGRKL FYVHYIDFNK RLDEWVTHER LDLKKIQFPK KEAKTPTKNG LPGSRPGSPE REVPASAQAS GKTLPIPVQI TLRFNLPKER EAIPGGEPDQ PLSSSSCLQP NHRSTKRKVE VVSPATPVPS ETAPASVFPQ NGAARRAVAA QPGRKRKSNC LGTDEDSQDS SDGIPSAPRM TGSLVSDRSH DDIVTRMKNI ECIELGRHRL KPWYFSPYPQ ELTTLPVLYL CEFCLKYGRS LKCLQRHLTK CDLRHPPGNE IYRKGTISFF EIDGRKNKSY SQNLCLLAKC FLDHKTLYYD TDPFLFYVMT EYDCKGFHIV GYFSKEKEST EDYNVACILT LPPYQRRGYG KLLIEFSYEL SKVEGKTGTP EKPLSDLGLL SYRSYWSQTI LEILMGLKSE SGERPQITIN EISEITSIKK EDVISTLQYL NLINYYKGQY ILTLSEDIVD GHERAMLKRL LRIDSKCLHF TPKDWSKRGK W
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Histone acetyltransferase KAT5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Histone acetyltransferase KAT5 Protein

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