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SDS-PAGE separation of QP8906 followed by commassie total protein stain results in a primary band consistent with reported data for HDAC4. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human HDAC4 Protein

$ 398.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8906
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 227

Product NumberDescriptionPrice
QP8906-ec-100ug Size: 100 ug, Tag: GST
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8906-ec-10ug
Recombinant Human HDAC4 Protein General Information
Alternate Names
HDAC4; HA6116; HDAC-4; AHO3; HD4; BDMR; HDAC-A; HDACA
Curated Database and Bioinformatic Data
Gene SymbolHDAC4
Entrez Gene ID9759
Ensemble Gene IDENSG00000068024
RefSeq Protein Accession(s)NP_006028.2
RefSeq mRNA Accession(s)NM_006037.3
UniProt ID(s)P56524
UniGene ID(s)Hs.20516
HGNC ID(s)HGNC:14063
COSMIC ID Link(s)HDAC4
KEGG Gene ID(s)hsa:9759
PharmGKB ID(s)PA29229
General Description of Recombinant Human HDAC4 Protein.
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Human HDAC4 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant HDAC4 based upon sequence from: Human
Host: QP8906 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) HDAC4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8906.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - His227
Amino Acid Sequence: MSSQSHPDGL SGRDQPVELL NPARVNHMPS TVDVATALPL QVAPSAVPMD LRLDHQFSLP VAEPALREQQ LQQELLALKQ KQQIQRQILI AEFQRQHEQL SRQHEAQLHE HIKQQQEMLA MKHQQELLEH QRKLERHRQE QELEKQHREQ KLQQLKNKEK GKESAVASTE VKMKLQEFVL NKKKALAHRN LNHCISSDPR YWYGKTQHSS LDQSSPPQSG VSTSYNH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human HDAC4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human HDAC4 Protein