SDS-PAGE separation of QP8908 followed by commassie total protein stain results in a primary band consistent with reported data for Histone deacetylase 7. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Histone deacetylase 7 Protein

$ 398.00 – $ 1,728.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP8908
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 164

Product Number	Description	Price
QP8908-ec-100ug	Size: 100 ug, Tag: His	$ 398.00
QP8908-ec-1mg	Size: 1 mg, Tag: His	$ 1,728.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP8908-ec-10ug

Recombinant Human Histone deacetylase 7 Protein (1-164aa) General Information
Alternate Names
HD7; HDAC7A; HD7A
Curated Database and Bioinformatic Data
Gene Symbol	HDAC7
Entrez Gene ID	51564
Ensemble Gene ID	ENSG00000061273
RefSeq Protein Accession(s)	NP_001091886.1
RefSeq mRNA Accession(s)	NM_001098416.3, NM_001308090.1, NM_015401.4, XM_011538481.1, XM_011538482.1
UniProt ID(s)	Q8WUI4
UniGene ID(s)	Hs.200063
HGNC ID(s)	HGNC:14067
COSMIC ID Link(s)	HDAC7
KEGG Gene ID(s)	hsa:51564
PharmGKB ID(s)	PA162390579
General Description of Recombinant Human Histone deacetylase 7 Protein (1-164aa).
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors . May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 .

Human Histone deacetylase 7 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Histone deacetylase 7 based upon sequence from: Human

Host: QP8908 protein expressed in E. coli.

Tag: His

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Histone deacetylase 7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP8908.

Bioactivity Data: Untested

Full Length? Partial (see sequence information for more details).

Expression Region: Met1 - Lys164

Amino Acid Sequence: MDLRVGQRPP VEPPPEPTLL ALQRPQRLHH HLFLAGLQQQ RSVEPMRLSM DTPMPELQVG PQEQELRQLL HKDKSKRSAV ASSVVKQKLA EVILKKQQAA LERTVHPNSP GIPYRTLEPL ETEGATRSML SSFLPPVPSL PSDPPEHFPL RKTVSEPNLK LRYK

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human Histone deacetylase 7 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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