SDS-PAGE separation of QP8951 followed by commassie total protein stain results in a primary band consistent with reported data for A2M / CPAMD5 / Alpha-2-macroglobulin. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Rat A2M / CPAMD5 / Alpha-2-macroglobulin Protein

$ 578.00$ 1,588.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8951
Species: Rat
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 131

Product NumberDescriptionPrice
QP8951-ye-100ug Size: 100 ug, Tag: His $ 578.00
QP8951-ye-500ug Size: 500 ug, Tag: His $ 1,588.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8951-ye-10ug
Recombinant Rat A2M / CPAMD5 / Alpha-2-macroglobulin Protein General Information
Alternate Names
A2M; CPAMD5; Alpha-2-macroglobulin; FWP007; S863-7; A2MD; CPAMD5
Curated Database and Bioinformatic Data
Gene SymbolA2m
Entrez Gene ID100911545
Ensemble Gene IDENSRNOG00000028896
RefSeq Protein Accession(s)NP_036620.2
RefSeq mRNA Accession(s)NM_012488.2, XM_003749828.2
UniProt ID(s)P06238
UniGene ID(s)Rn.225884
COSMIC ID Link(s)A2m
KEGG Gene ID(s)rno:100911545
General Description of Recombinant Rat A2M / CPAMD5 / Alpha-2-macroglobulin Protein.
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme rains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Rat A2M / CPAMD5 / Alpha-2-macroglobulin Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant A2M / CPAMD5 / Alpha-2-macroglobulin based upon sequence from: Rat
Host: QP8951 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) A2M / CPAMD5 / Alpha-2-macroglobulin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8951.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Leu620 - Ala750
Amino Acid Sequence: LIYDLLPVKD LTGFPQGADQ REEDTNGCVK QNDTYINGIL YSPVQNTNEE DMYGFLKDMG LKVFTNSNIR KPKVCERLRD NKGIPAAYHL VSQSHMDAFL ESSESPTETR RSYFPETWIW DLVVVDSAGV A
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Rat A2M / CPAMD5 / Alpha-2-macroglobulin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Rat A2M / CPAMD5 / Alpha-2-macroglobulin Protein