SDS-PAGE separation of QP8984 followed by commassie total protein stain results in a primary band consistent with reported data for Apoptotic protease-activating factor 1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Apoptotic protease-activating factor 1 Protein

$ 688.00$ 1,918.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8984
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 312

Product NumberDescriptionPrice
QP8984-ye-100ug Size: 100 ug, Tag: His $ 688.00
QP8984-ye-500ug Size: 500 ug, Tag: His $ 1,918.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8984-ye-10ug
Recombinant Human Apoptotic protease-activating factor 1 Protein General Information
Alternate Names
APAF-1; CED4
Curated Database and Bioinformatic Data
Gene SymbolAPAF1
Entrez Gene ID317
Ensemble Gene IDENSG00000120868
RefSeq Protein Accession(s)NP_001151.1
RefSeq mRNA Accession(s)NM_001160.2, NM_013229.2, NM_181861.1, NM_181868.1, NM_181869.1
UniProt ID(s)O14727
UniGene ID(s)Hs.552567
HGNC ID(s)HGNC:576
COSMIC ID Link(s)APAF1
KEGG Gene ID(s)hsa:317
PharmGKB ID(s)PA24868
General Description of Recombinant Human Apoptotic protease-activating factor 1 Protein.
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Human Apoptotic protease-activating factor 1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Apoptotic protease-activating factor 1 based upon sequence from: Human
Host: QP8984 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Apoptotic protease-activating factor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8984.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser104 - Leu415
Amino Acid Sequence: SGITSYVRTV LCEGGVPQRP VVFVTRKKLV NAIQQKLSKL KGEPGWVTIH GMAGCGKSVL AAEAVRDHSL LEGCFPGGVH WVSVGKQDKS GLLMKLQNLC TRLDQDESFS QRLPLNIEEA KDRLRILMLR KHPRSLLILD DVWDSWVLKA FDSQCQILLT TRDKSVTDSV MGPKYVVPVE SSLGKEKGLE ILSLFVNMKK ADLPEQAHSI IKECKGSPLV VSLIGALLRD FPNRWEYYLK QLQNKQFKRI RKSSSYDYEA LDEAMSISVE MLREDIKDYY TDLSILQKDV KVPTKVLCIL WDMETEEVED IL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Apoptotic protease-activating factor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Apoptotic protease-activating factor 1 Protein