SDS-PAGE separation of QP9010 followed by commassie total protein stain results in a primary band consistent with reported data for BNIP3L. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human BNIP3L Protein

$ 528.00$ 1,458.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9010
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 219

Product NumberDescriptionPrice
QP9010-ye-100ug Size: 100 ug, Tag: His $ 528.00
QP9010-ye-500ug Size: 500 ug, Tag: His $ 1,458.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9010-ye-10ug
Recombinant Human BNIP3L Protein General Information
Alternate Names
NIX; BNIP3a; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-li
Curated Database and Bioinformatic Data
Gene SymbolBNIP3L
Entrez Gene ID665
Ensemble Gene IDENSG00000104765
RefSeq Protein Accession(s)NP_001317420.1
RefSeq mRNA Accession(s)NM_001330491.1, NM_004331.2
UniProt ID(s)O60238
UniGene ID(s)Hs.131226
HGNC ID(s)HGNC:1085
COSMIC ID Link(s)BNIP3L
KEGG Gene ID(s)hsa:665
PharmGKB ID(s)PA25395
General Description of Recombinant Human BNIP3L Protein.
Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.

Human BNIP3L Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant BNIP3L based upon sequence from: Human
Host: QP9010 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) BNIP3L, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9010.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Tyr219
Amino Acid Sequence: MSSHLVEPPP PLHNNNNNCE ENEQSLPPPA GLNSSWVELP MNSSNGNDNG NGKNGGLEHV PSSSSIHNGD MEKILLDAQH ESGQSSSRGS SHCDSPSPQE DGQIMFDVEM HTSRDHSSQS EEEVVEGEKE VEALKKSADW VSDWSSRPEN IPPKEFHFRH PKRSVSLSMR KSGAMKKGGI FSAEFLKVFI PSLFLSHVLA LGLGIYIGKR LSTPSASTY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human BNIP3L Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human BNIP3L Protein