SDS-PAGE separation of QP9081 followed by commassie total protein stain results in a primary band consistent with reported data for M-CSF / CSF-1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human M-CSF / CSF-1 Protein

Please Select Product Options Below To View The Catalog Number.

SKU: QP9081
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 522

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On Demand Protein: 3-5 Week Lead Time. (Why?)
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9081-ye-10ug
Recombinant Human M-CSF / CSF-1 Protein General Information
Alternate Names
M-CSF; CSF-1; C87615; MCSF; Csfm
Curated Database and Bioinformatic Data
Gene SymbolCSF1
Entrez Gene ID1435
Ensemble Gene IDENSG00000184371
RefSeq Protein Accession(s)NP_000748.3
RefSeq mRNA Accession(s)NM_000757.5, NM_172210.2, NM_172211.3, NM_172212.2
UniProt ID(s)P09603
UniGene ID(s)Hs.173894
HGNC ID(s)HGNC:2432
COSMIC ID Link(s)CSF1
KEGG Gene ID(s)hsa:1435
PharmGKB ID(s)PA26935
General Description of Recombinant Human M-CSF / CSF-1 Protein.
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hatopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and fale fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of mbrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

Human M-CSF / CSF-1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant M-CSF / CSF-1 based upon sequence from: Human
Host: QP9081 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) M-CSF / CSF-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9081.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu33 - Val554
Amino Acid Sequence: EEVSEYCSHM IGSGHLQSLQ RLIDSQMETS CQITFEFVDQ EQLKDPVCYL KKAFLLVQDI MEDTMRFRDN TPNAIAIVQL QELSLRLKSC FTKDYEEHDK ACVRTFYETP LQLLEKVKNV FNETKNLLDK DWNIFSKNCN NSFAECSSQD VVTKPDCNCL YPKAIPSSDP ASVSPHQPLA PSMAPVAGLT WEDSEGTEGS SLLPGEQPLH TVDPGSAKQR PPRSTCQSFE PPETPVVKDS TIGGSPQPRP SVGAFNPGME DILDSAMGTN WVPEEASGEA SEIPVPQGTE LSPSRPGGGS MQTEPARPSN FLSASSPLPA SAKGQQPADV TGTALPRVGP VRPTGQDWNH TPQKTDHPSA LLRDPPEPGS PRISSLRPQG LSNPSTLSAQ PQLSRSHSSG SVLPLGELEG RRSTRDRRSP AEPEGGPASE GAARPLPRFN SVPLTDTGHE RQSEGSFSPQ LQESVFHLLV PSVILVLLAV GGLLFYRWRR RSHQEPQRAD SPLEQPEGSP LTQDDRQVEL PV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human M-CSF / CSF-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human M-CSF / CSF-1 Protein