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SDS-PAGE separation of QP9230 followed by commassie total protein stain results in a primary band consistent with reported data for Potassium channel subfamily K member 2. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Potassium channel subfamily K member 2 Protein

$ 468.00 – $ 1,298.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9230
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 143

Product NumberDescriptionPrice
QP9230-ye-100ug Size: 100 ug, Tag: His $ 468.00
QP9230-ye-500ug Size: 500 ug, Tag: His $ 1,298.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9230-ye-10ug
Recombinant Human Potassium channel subfamily K member 2 Protein General Information
Alternate Names
K2p2.1; TREK; hTREK-1c; TPKC1; hTREK-1e; TREK-1; TREK1
Curated Database and Bioinformatic Data
Gene SymbolKCNK2
Entrez Gene ID3776
Ensemble Gene IDENSG00000082482
RefSeq Protein Accession(s)NP_001017424.1
RefSeq mRNA Accession(s)NM_001017424.2, NM_001017425.2, NM_014217.3, XM_017001248.1
UniProt ID(s)O95069
UniGene ID(s)Hs.497745
HGNC ID(s)HGNC:6277
COSMIC ID Link(s)KCNK2
KEGG Gene ID(s)hsa:3776
PharmGKB ID(s)PA30059
General Description of Recombinant Human Potassium channel subfamily K member 2 Protein.
Ion channel that contributes to passive transmembrane potassium transport (PubMed:23169818). Reversibly converts between a voltage-insensitive potassium leak channel and a voltage-dependent outward rectifying potassium channel in a phosphorylation-dependent manner (PubMed:11319556). In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled receptors, such as F2R and CNR1

Human Potassium channel subfamily K member 2 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Potassium channel subfamily K member 2 based upon sequence from: Human
Host: QP9230 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Potassium channel subfamily K member 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9230.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - Asp143
Amino Acid Sequence: MLPSASRERP GYRAGVAAPD LLDPKSAAQN SKPRLSFSTK PTVLASRVES DTTINVMKWK TVSTIFLVVV LYLIIGATVF KALEQPHEIS QRTTIVIQKQ TFISQHSCVN STELDELIQQ IVAAINAGII PLGNTSNQIS HWD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Potassium channel subfamily K member 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Potassium channel subfamily K member 2 Protein