PDF DatasheetHuman Nestin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Nestin based upon sequence from: Human
Host: QP9304 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Nestin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9304.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Pro1321 – Leu1569
Amino Acid Sequence: PPPQGETGKE GWDPAVLASE GLEAPPSEKE EGEEGEEECG RDSDLSEEFE DLGTEAPFLP GVPGEVAEPL GQVPQLLLDP AAWDRDGESD GFADEEESGE EGEEDQEEGR EPGAGRWGPG SSVGSLQALS SSQRGEFLES DSVSVSVPWD DSLRGAVAGA PKTALETESQ DSAEPSGSEE ESDPVSLERE DKVPGPLEIP SGMEDAGPGA DIIGVNGQGP NLEGKSQHVN GGVMNGLEQS EEVGQGMPL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Nestin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Nestin Protein General Information | |
|---|---|
| Alternate Names | |
| Nbla00170 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NES |
| Entrez Gene ID | 10763 |
| Ensemble Gene ID | ENSG00000132688 |
| RefSeq Protein Accession(s) | NP_006608.1 |
| RefSeq mRNA Accession(s) | NM_006617.1 |
| UniProt ID(s) | P48681 |
| UniGene ID(s) | Hs.527971 |
| HGNC ID(s) | HGNC:7756 |
| COSMIC ID Link(s) | NES |
| KEGG Gene ID(s) | hsa:10763 |
| PharmGKB ID(s) | PA31556 |
| General Description of Recombinant Human Nestin Protein. | |
| Required for brain and eye development. Promotes the disassbly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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