SDS-PAGE separation of QP9341 followed by commassie total protein stain results in a primary band consistent with reported data for Protein phosphatase 1 regulatory subunit 15A. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Protein phosphatase 1 regulatory subunit 15A Protein

$ 688.00$ 1,918.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9341
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 635

Product NumberDescriptionPrice
QP9341-ye-100ug Size: 100 ug, Tag: His $ 688.00
QP9341-ye-500ug Size: 500 ug, Tag: His $ 1,918.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9341-ye-10ug
Recombinant Human Protein phosphatase 1 regulatory subunit 15A Protein General Information
Alternate Names
GADD34
Curated Database and Bioinformatic Data
Gene SymbolPPP1R15A
Entrez Gene ID23645
Ensemble Gene IDENSG00000087074
RefSeq Protein Accession(s)NP_055145.3
RefSeq mRNA Accession(s)NM_014330.3
UniProt ID(s)O75807
UniGene ID(s)Hs.631593
HGNC ID(s)HGNC:14375
COSMIC ID Link(s)PPP1R15A
KEGG Gene ID(s)hsa:23645
PharmGKB ID(s)PA33632
General Description of Recombinant Human Protein phosphatase 1 regulatory subunit 15A Protein.
Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

Human Protein phosphatase 1 regulatory subunit 15A Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Protein phosphatase 1 regulatory subunit 15A based upon sequence from: Human
Host: QP9341 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Protein phosphatase 1 regulatory subunit 15A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9341.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Gly40 - Gly674
Amino Acid Sequence: GPLEPWLVEA VKGAALVEAG LEGEARTPLA IPHTPWGRRP EEEAEDSGGP GEDRETLGLK TSSSLPEAWG LLDDDDGMYG EREATSVPRG QGSQFADGQR APLSPSLLIR TLQGSDKNPG EEKAEEEGVA EEEGVNKFSY PPSHRECCPA VEEEDDEEAV KKEAHRTSTS ALSPGSKPST WVSCPGEEEN QATEDKRTER SKGARKTSVS PRSSGSDPRS WEYRSGEASE EKEEKAHKET GKGEAAPGPQ SSAPAQRPQL KSWWCQPSDE EEGEVKALGA AEKDGEAECP PCIPPPSAFL KAWVYWPGED TEEEEDEEED EDSDSGSDEE EGEAEASSST PATGVFLKSW VYQPGEDTEE EEDEDSDTGS AEDEREAETS ASTPPASAFL KAWVYRPGED TEEEEDEDVD SEDKEDDSEA ALGEAESDPH PSHPDQRAHF RGWGYRPGKE TEEEEAAEDW GEAEPCPFRV AIYVPGEKPP PPWAPPRLPL RLQRRLKRPE TPTHDPDPET PLKARKVRFS EKVTVHFLAV WAGPAQAARQ GPWEQLARDR SRFARRITQA QEELSPCLTP AARARAWARL RNPPLAPIPA LTQTLPSSSV PSSPVQTTPL SMS-QAVATP SRSSAAAAAA LDLSGRRG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Protein phosphatase 1 regulatory subunit 15A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Protein phosphatase 1 regulatory subunit 15A Protein