SDS-PAGE separation of QP9356 followed by commassie total protein stain results in a primary band consistent with reported data for CD45 / PTPRC. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human CD45 / PTPRC Protein

$ 468.00$ 1,298.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9356
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 552

Product NumberDescriptionPrice
QP9356-ye-100ug Size: 100 ug, Tag: His $ 468.00
QP9356-ye-500ug Size: 500 ug, Tag: His $ 1,298.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9356-ye-10ug
Recombinant Human CD45 / PTPRC Protein General Information
Alternate Names
CD45; PTPRC; Lyt-4; T200; loc; CD45R; Ly-5; B220; Cd45; L-CA
Curated Database and Bioinformatic Data
Gene SymbolPTPRC
Entrez Gene ID5788
Ensemble Gene IDENSG00000081237
RefSeq Protein Accession(s)NP_002829.3
RefSeq mRNA Accession(s)NM_002838.4, NM_080921.3
UniProt ID(s)P08575
UniGene ID(s)Hs.654514
HGNC ID(s)HGNC:9666
COSMIC ID Link(s)PTPRC
KEGG Gene ID(s)hsa:5788
PharmGKB ID(s)PA34011
General Description of Recombinant Human CD45 / PTPRC Protein.
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one ses to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity .

Human CD45 / PTPRC Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant CD45 / PTPRC based upon sequence from: Human
Host: QP9356 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CD45 / PTPRC, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9356.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Gln24 - Lys575
Amino Acid Sequence: QSPTPSPTGL TTAKMPSVPL SSDPLPTHTT AFSPASTFER ENDFSETTTS LSPDNTSTQV SPDSLDNASA FNTTGVSSVQ TPHLPTHADS QTPSAGTDTQ TFSGSAANAK LNPTPGSNAI SDVPGERSTA STFPTDPVSP LTTTLSLAHH SSAALPARTS NTTITANTSD AYLNASETTT LSPSGSAVIS TTTIATTPSK PTCDEKYANI TVDYLYNKET KLFTAKLNVN ENVECGNNTC TNNEVHNLTE CKNASVSISH NSCTAPDKTL ILDVPPGVEK FQLHDCTQVE KADTTICLKW KNIETFTCDT QNITYRFQCG NMIFDNKEIK LENLEPEHEY KCDSEILYNN HKFTNASKII KTDFGSPGEP QIIFCRSEAA HQGVITWNPP QRSFHNFTLC YIKETEKDCL NLDKNLIKYD LQNLKPYTKY VLSLHAYIIA KVQRNGSAAM CHFTTKSAPP SQVWNMTVSM TSDNSMHVKC RPPRDRNGPH ERYHLEVEAG NTLVRNESHK NCDFRVKDLQ YSTDYTFKAY FHNGDYPGEP FILHHSTSYN SK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CD45 / PTPRC Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human CD45 / PTPRC Protein