SDS-PAGE separation of QP9370 followed by commassie total protein stain results in a primary band consistent with reported data for RING finger protein 11. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human RING finger protein 11

$ 188.00$ 2,008.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9370
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 153

Product NumberDescriptionPrice
QP9370-ye-10ug Size: 10 ug, Tag: His $ 188.00
QP9370-ye-100ug Size: 100 ug, Tag: His $ 468.00
QP9370-ye-1mg Size: 1 mg, Tag: His $ 2,008.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9370-ye-10ug
Recombinant Human RING finger protein 11 Protein General Information
Alternate Names
SID1669; CGI-123
Curated Database and Bioinformatic Data
Gene SymbolRNF11
Entrez Gene ID26994
Ensemble Gene IDENSG00000123091
RefSeq Protein Accession(s)NP_055187.1
RefSeq mRNA Accession(s)NM_014372.4
UniProt ID(s)Q9Y3C5
UniGene ID(s)Hs.309641
HGNC ID(s)HGNC:10056
COSMIC ID Link(s)RNF11
KEGG Gene ID(s)hsa:26994
PharmGKB ID(s)PA34420
General Description of Recombinant Human RING finger protein 11 Protein.
Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation. TNFAIP3 deubiquitinates 'Lys-63' polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Recruits STAMBP to the E3 ubiquitin-ligase SMURF2 for ubiquitination, leading to its degradation by the 26S proteasome.

Human RING finger protein 11 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant RING finger protein 11 based upon sequence from: Human
Host: QP9370 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) RING finger protein 11, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9370.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly2 - Asn154
Amino Acid Sequence: GNCLKSPTSD DISLLHESQS DRASFGEGTE PDQEPPPPYQ EQVPVPVYHP TPSQTRLATQ LTEEEQIRIA QRIGLIQHLP KGVYDPGRDG SEKKIRECVI CMMDFVYGDP IRFLPCMHIY HLDCIDDWLM RSFTCPSCME PVDAALLSSY ETN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human RING finger protein 11 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human RING finger protein 11