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Recombinant Human UDP-glucuronosyltransferase 1-1 Protein

$ 468.00$ 1,298.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9458
Species: Human
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 508

Product NumberDescriptionPrice
QP9458-ye-100ug Size: 100 ug, Tag: His $ 468.00
QP9458-ye-500ug Size: 500 ug, Tag: His $ 1,298.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9458-ye-10ug
Recombinant Human UDP-glucuronosyltransferase 1-1 Protein General Information
Alternate Names
UDPGT; UDPGT 1-1; BILIQTL1; UGT1A; HUG-BR1; UGT1; GNT1
Curated Database and Bioinformatic Data
Gene SymbolUGT1A1
Entrez Gene ID54658
Ensemble Gene IDENSG00000241635
RefSeq Protein Accession(s)NP_000454.1
RefSeq mRNA Accession(s)NM_000463.2
UniProt ID(s)P22309
UniGene ID(s)Hs.554822
HGNC ID(s)HGNC:12530
COSMIC ID Link(s)UGT1A1
KEGG Gene ID(s)hsa:54658
PharmGKB ID(s)PA37181
General Description of Recombinant Human UDP-glucuronosyltransferase 1-1 Protein.
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.

Human UDP-glucuronosyltransferase 1-1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant UDP-glucuronosyltransferase 1-1 based upon sequence from: Human
Host: QP9458 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) UDP-glucuronosyltransferase 1-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9458.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: His26 - His533
Amino Acid Sequence: HAGKILLIPV DGSHWLSMLG AIQQLQQRGH EIVVLAPDAS LYIRDGAFYT LKTYPVPFQR EDVKESFVSL GHNVFENDSF LQRVIKTYKK IKKDSAMLLS GCSHLLHNKE LMASLAESSF DVMLTDPFLP CSPIVAQYLS LPTVFFLHAL PCSLEFEATQ CPNPFSYVPR PLSSHSDHMT FLQRVKNMLI AFSQNFLCDV VYSPYATLAS EFLQREVTVQ DLLSSASVWL FRSDFVKDYP RPIMPNMVFV GGINCLHQNP LSQEFEAYIN ASGEHGIVVF SLGSMVSEIP EKKAMAIADA LGKIPQTVLW RYTGTRPSNL ANNTILVKWL PQNDLLGHPM TRAFITHAGS HGVYESICNG VPMVMMPLFG DQMDNAKRME TKGAGVTLNV LEMTSEDLEN ALKAVINDKS YKENIMRLSS LHKDRPVEPL DLAVFWVEFV MRHKGAPHLR PAAHDLTWYQ YHSLDVIGFL LAVVLTVAFI TFKCCAYGYR KCLGKKGRVK KAHKSKTH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human UDP-glucuronosyltransferase 1-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human UDP-glucuronosyltransferase 1-1 Protein