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Recombinant Rotavirus Non-structural glycoprotein 1

$ 328.00$ 2,958.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP9696
Species: Rotavirus
Available Tags: His
Host: Yeast
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 124

Product NumberDescriptionPrice
QP9696-ye-10ug Size: 10 ug, Tag: His $ 328.00
QP9696-ye-50ug Size: 50 ug, Tag: His $ 458.00
QP9696-ye-100ug Size: 100 ug, Tag: His $ 798.00
QP9696-ye-200ug Size: 200 ug, Tag: His $ 1,318.00
QP9696-ye-500ug Size: 500 ug, Tag: His $ 1,858.00
QP9696-ye-1mg Size: 1 mg, Tag: His $ 2,958.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP9696-ye-10ug
Recombinant Rotavirus Non-structural glycoprotein 4 Protein (52-175aa) General Information
Curated Database and Bioinformatic Data
Gene SymbolNSP4
UniProt ID(s)Q82035
General Description of Recombinant Rotavirus Non-structural glycoprotein 4 Protein (52-175aa).
Involved in virus morphogenesis. Functions as a receptor for the immature double-layered inner capsid particle (ICP) which transiently buds into the lumen of the rough endoplasmic reticulum during viral maturation .Enterotoxin that causes a phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells. Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability. Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea. To perform this enterotoxigenic role in vivo, NSP4 is probably released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with the plasma mbrane receptors on neighboring epithelial cells. Possible receptors for NSP4 are alpha-1/beta-1 and alpha-2/beta-1 integrin heterodimers .

Rotavirus Non-structural glycoprotein 4 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Non-structural glycoprotein 4 based upon sequence from: Rotavirus
Host: QP9696 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Rotavirus A (strain Human/United Kingdom/ST3/1975 G4-P2A[6]-I1-R1-C1-M1-A1-N1-T1-E1-H1) (RV-A) (Rotavirus A (strain St. Thomas 3)) Non-structural glycoprotein 4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9696.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Pro52 - Met175
Amino Acid Sequence: PTMKIALKAS KCSYKVIKYC VVTIINTLLK LAGYKEQVTT KDEIEQQMDR IVKEMRRQLE MIDKLTTREI EQIELLKRIH DNLITRPVNV IDMSMEFNQK NIKTLDEWES RKNPYEPSEV TASM
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Rotavirus Non-structural glycoprotein 4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Rotavirus Non-structural glycoprotein 1